The fact that they want 10 years of experience and you don’t have them is a problem. But it’s not one that can’t be overcome.
First of all, if you only have two years it might not be a good idea to apply, as you actually might not be qualified. But if you have four or five years and you’ve accomplished a ton in that time, then go for it. But do it by touting those accomplishments.
Highlight the project you worked on that led to a huge increase in product sales, or the cost-cutting initiative you spearheaded that saved $2 million annually. If you have enough clear-cut examples of tangible accomplishments, it’ll often be enough to make up for the years of experience you lack.