Associate/Staff Scientist - In Vivo Immunology

Access to Advanced Health Institute
Seattle, WA Full Time
POSTED ON 3/7/2023 CLOSED ON 5/9/2023

What are the responsibilities and job description for the Associate/Staff Scientist - In Vivo Immunology position at Access to Advanced Health Institute?

Access to Advanced Health Institute is a Seattle-based nonprofit biotech institute that is undergoing a transformation to lead a global coalition to fight infectious diseases and address health disparities and inequities worldwide. We think it’s unfair that where a person lives or how much money they make dictates their access to life-changing medicine. We’re looking for people who want to join us in increasing accessibility to tools that harness the immune system and allow a healthy life, free of illness and disease, regardless of geography or socio-economic status - from compassion and collaboration comes change.

We will serve as a center for innovation and collaboration in vaccine and cancer immunotherapy research and development, early-phase GMP manufacturing, and training the next generation of scientists and manufacturing teams to achieve our mission. This is where the high-quality science of an academic research organization and the product-development capabilities of a biotech company meet.

Summary:
AAHI is seeking a highly motivated scientist to join our RNA Platform team. The successful candidate will direct the in vivo mouse immunology studies on the RNA Team, providing additional support as necessary to conduct in vivo aspects of product stability and release testing studies for AAHI’s Product Development and GMP teams as necessary. The successful candidate will aid in finalizing in vivo study designs alongside other RNA team Ph.D. staff. This role will involve the coordination of AAHI Research Associates’ effort for the studies’ successful, high-quality completion, and will include Research Associate mentorship and supervision. The Staff Scientist will ensure that all job responsibilities are performed and documented accurately and on time.

An exact title is to be determined based on qualifications and experience:
  • Associate Scientist range: $80000 - $100,000 per year.
  • Staff Scientist range: $100,000 - $123,000 per year.

Responsibilities:
  • In vivo mouse study design and execution.
  • Preparation of animal tissue specimens for ex vivo assays under BSL2 conditions.
  • Perform immunoassays such as intracellular cytokine staining, flow cytometry, ELISpot, ELISA, etc.
  • Coordination of a team of Research Associates of varying abilities and experience levels for the execution of in vivo studies.
  • Primary supervision and mentorship of Research Associates.
  • Utilize graphing programs, and statistical methods to compile and analyze data.
  • Responsible for performing assay development, optimizations, and validations as a primary lead and/or in collaboration with others.
  • Records procedures, outcomes, and observations in lab notebook following established guidelines.
  • Monitors laboratory supply inventories and works with purchasing to ensure available stock for the group or area.
  • Presents research at group meetings and assists in drafting study reports, manuscripts, etc.
  • Collaborates with internal and external team members, and provides training and mentoring to junior associates.
  • Communicates with research management on a regular basis.
  • Contributes to or leads maintenance of the sample repository including sample tracking procedures.

This summary describes a portion of the essential functions/responsibilities of this position. It is not an exhaustive list of all job duties.

Requirements:
Education:
  • B.S. and 8 years experience, or M.S. and 6 years experience, or Ph.D. in immunology, vaccinology, or closely related field and 4 years experience.
  • Proficiency with mouse models of responses to vaccination is required, including extensive hands-on mouse-handling experience and the ability to train others.
  • Proficiency with flow cytometry, ELISA, ELISpot, and/or other immunoassays is required.
  • Experience with analyzing innate and adaptive immunity in animal models.
  • Experience and skills with mouse immunogenicity study design, humoral and/or cellular immunology assays, and vaccine immunogenicity.
  • Proficiency in vivo imaging, and in vitro assays is preferred.
  • Working knowledge of flow cytometry and experience using FlowJo analysis software.
  • Must be self-motivated, highly organized, and team-oriented.
  • Proficiency in MS Office and scientific data/graphing software.

Benefits:
We offer a comprehensive compensation plan which includes:
  • Medical, Dental, and Vision.
  • Up to 6 weeks' Vacation & Sick pay.
  • Group Life, AD&D, Short & Long-term disability, Hospital Indemnity, Accident.
  • Flexible Spending Accounts (HSA and Dependent Care).
  • Matching 401(k) Retirement Plan.
  • Commuter benefits.
  • Employee Assistance Plan (EAP).
  • Flexible work schedule.
  • Mindfulness/Fitness App Subscription.
  • Voluntary & Lifestyle Benefits.

Vaccination Requirement:
Due to the threat of more infectious and deadly COVID-19 variant strains emerging, we recently announced a new mandatory vaccination policy requiring our employees to be fully vaccinated against COVID-19 as a condition of employment. We will make reasonable accommodations for valid exemptions based on disability, medical, or religious reasons. With this policy, AAHI joins a growing list of companies that are prioritizing sound science and available facts to best ensure the ongoing safety of employees and the community.

We do not discriminate. We are an equal opportunity employer and are committed to inclusion and encourage everyone to bring their full selves to work. We are an E-Verify Employer.

Salary : $80,000 - $123,000

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