Associate Director, Health Economics & Outcomes Research (HEOR)

Agios Pharmaceuticals Inc
Agios Pharmaceuticals HQ, MA Remote Full Time
POSTED ON 10/4/2022 CLOSED ON 12/19/2022

Job Posting for Associate Director, Health Economics & Outcomes Research (HEOR) at Agios Pharmaceuticals Inc

Associate Director, HEOR

Who we are:

Agios is a biopharmaceutical company that is fueled by connections. We thrive in a supportive, fun, and flexible environment full of people empowered to bring their whole selves to work. We care deeply about our work, each other, and the patients who count on us. Our teams cultivate strong bonds with patient communities, healthcare professionals, partners and colleagues, which helps us discover, develop and deliver therapies for genetically defined diseases – and make a bigger difference in their lives. In the U.S., Agios markets a first-in-class pyruvate kinase (PK) activator for the treatment of hemolytic anemia in adults with PK deficiency. Building on the company’s leadership in the field of cellular metabolism, Agios is advancing a robust clinical pipeline of investigational medicines with active and planned programs in alpha- and beta-thalassemia, sickle cell disease, pediatric PK deficiency and MDS-associated anemia. In addition to its clinical pipeline, Agios has multiple investigational therapies in preclinical development and an industry-leading research team with unmatched expertise in cellular metabolism and genetics.

The impact you will make:

Agios Pharmaceuticals is searching for a dynamic Associate Director, HEOR to join our growing HEOR team. We want someone who cares about this important work, and who’s driven to connect to our mission of helping these patient communities. The Associate Director, HEOR will be responsible for playing an integral role in the development and commercialization activities for mitapivat and other early phase assets. The HEOR team at Agios is responsible for three pillars of activities:

  • Real world evidence generation (e.g. studies of natural history, burden of illness, treatment patterns, etc. using a variety of data sources including EMR, claims data, registries, chart reviews, and qualitative research);
  • Market access support (e.g. Payer and HTA landscape research, cost-effectiveness and budget impact modeling, AMCP and global value dossiers); and,
  • Clinical development program support (e.g. patient-reported outcomes (PRO) strategies for clinical trials).

What you will do:

As a member of the HEOR team, the successful candidate will be responsible for leading tactical execution of HEOR strategies across all three pillars of activities. They will also partner closely with the HEOR team’s patient-centered research lead to ensure our in-trial and ex-trial patient-reported outcomes and qualitative research activities align with the programs’ broader HEOR strategies.  Demonstrated experience generating real-world evidence with US data sources is required. Additionally, experience in creating a PRO strategy for clinical trials, conducting systematic literature reviews, and economic modeling skills and experience developing budget impact or cost-effectiveness models are required. This role will be accountable for designing and conducting superior quality research that is medically relevant, scientifically valid, and aligned with the evidence generation and communication needs of the program.   The position is best suited for an individual who has the skills and drive to lead all HEOR activities for launch in the US and globally.

The ideal candidate has HEOR training and experience to independently manage a broad spectrum of projects.  The dynamics of our teams and the culture of the organization offer unique opportunities for growth and development by allowing individuals to stretch outside of the typical boundaries of HEOR activities.  This role will report to the Director of Health Economics & Outcomes Research.

  • Work closely with Clinical Development, Medical Affairs, Commercial, and Market Access teams to understand the HEOR needs of the business
  • Design, implement, and manage health economics and outcomes research projects, including but not limited to retrospective database analyses, HTA- or ICER-grade economic models and budget impact models, epidemiological research, and systematic literature reviews
  • Inform PRO strategies for early phase assets
  • Collaborate with cross-functional partners on the development of product value propositions 
  • Prepare global value dossiers and synthesize evidence
  • Present health economics and outcomes research findings at scientific congresses and participate in the development and writing of manuscripts for publication in peer-reviewed journals
  • Translate output from HEOR initiatives into tools and resources for field teams
  • Provide HEOR functional expertise on cross-functional strategy teams
  • Manage relationships and budgets with vendors to ensure timely completion of high quality, customer-relevant projects
  • Maintain in-depth knowledge of the disease state, market & customer dynamics, the competitive landscape, and reimbursement issues
  • Build strong relationships with internal partners and ensure continuous and consistent communication regarding HEOR projects
  • Ensure compliance with all applicable laws, Agios policies, regulations and regulatory guidelines governing commercial and scientific interactions with healthcare professionals, payers, advocacy and other business partners.

What you bring:

  • Master’s or doctoral degree in health economics, pharmacy, epidemiology, health services research, public health, or related field
  • Minimum of 5 years of HEOR experience within consulting or industry, previous experience working in the academic or payer setting may be considered
  • Demonstrated technical excellence in designing, conducting, and interpreting health economics and outcomes research
  • Solid understanding of healthcare delivery systems and reimbursement processes for pharmaceuticals in the U.S. and major international markets
  • Demonstrated knowledge of evolving evidence requirements and the use of real-world evidence by regulators
  • Excellent written and verbal communication skills
  • Record of peer-reviewed publications
  • Strong interpersonal skills and ability to collaborate on cross-functional teams
  • Ability to navigate ambiguous, complex, and difficult situations
  • Ability to interface with multiple stakeholders, including clinicians and payers
  • Strong project management and time management skills

Preferred Qualifications:

  • Experience working in rare diseases
  • Product launch experience
  • Familiarity with machine learning/AI methods or experience with innovative databases

What we will give you:

  • Deliberate Development. Your professional growth as one of our top priorities.
  • Flexibility. We’re all about individual needs. We embrace different perspectives, work styles, health and wellness approaches, care of families and productivity. When you’re at your best, we’re at our best.
  • Premium benefits package. We invest in the health, wellbeing and security of our people with a premium benefits package that is well-rounded and flexible to help meet the varied personal and professional needs of every member of our team.
  • Competitive performance-based compensation. This includes both short- and long-term incentives that are connected to our business strategy.
  • Psychological safety.  We support an environment of fearlessness. We want you to share your ideas, speak candidly and take data-informed risks to help push the boundaries.
  • Commitment to diversity. We strive to foster a welcoming workplace where everyone can thrive. We’re continuously looking to improve the inclusivity of our workforce.
  • Commitment to community. We’re an active participant in the communities that surround us – the communities where we live, and the community of people and their loved ones in need of better treatment options for conditions that are often overlooked.

Interested in learning more about what makes our culture unique? Visit the Inside Agios section of our website.

Agios requires all new hires to be “fully vaccinated” against COVID-19, as defined by the Centers for Disease Control and Prevention (CDC) on or before their first day of work.  Individuals who have been offered employment who have a disability, medical condition, or sincerely-held religious belief, observance, or practice that prevents them from being vaccinated against COVID-19 are required to request and be granted a reasonable accommodation prior to their first day of work. 

 

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