What are the responsibilities and job description for the Principal Scientist Computational Chemist position at Merck & Company Inc?
Job Details
Job Description
Position Title
Principal Scientist, Computational Chemistry , West Point
Position Description
We are seeking a creative, self-motivated computational chemist with exceptional interpersonal and problem-solving skills to join the Modeling and Informatics team in West Point, PA, US .
M&I is a diverse and inclusive team of approximately 50 computational chemists and informaticians, who employ state of the art capabilities to drive drug design. We are an integral arm of both discovery and process chemistry and collaborate seamlessly with teams across the globe to innovate and invent better molecules faster . We are looking for a strategic thinker and accomplished computational drug hunter to take on a position that carries significant influence across our Company chemistry from target identification through delivery of clinical candidates in our Infectious Disease, Vaccine and Neuroscience portfolios .
Key responsibilities will include:
Scientific Innovation:
Building Relationships:
Strategy:
We recognize that the diversity in our team is our strength and are committed to creating an inclusive environment for all employees. Successful candidates must demonstrate inclusive behaviors in working with a diverse group of scientists to drive our core mission.
Because we believe our best collaboration opportunities occur in a face-to-face context, this position will be in person, on site in West Point, PA.
Position Qualifications :
Education Minimum Requirement:
Ph.D. or M.S. degree in chemistry, biochemistry, biophysics, or equivalent with a computational emphasis .
Required Experience and Skills:
Preferred Experience and Skills:
NOTICE FOR INTERNAL APPLICANTS
In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.
If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.
Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also with policies established by such external stakeholders (for example, a requirement to be vaccinated against COVID-19 in order to access a facility or meet with stakeholders). Please understand that, as permitted by applicable law, if you have not been vaccinated against COVID-19 and an essential function of your job is to call on external stakeholders who require vaccination to enter their premises or engage in face-to-face meetings, then your employment may pose an undue burden to business operations, in which case you may not be offered employment, or your employment could be terminated. Please also note that, where permitted by applicable law, the Company reserves the right to require COVID-19 vaccinations for positions, such as in Global Employee Health, where the Company determines in its discretion that the nature of the role presents an increased risk of disease transmission.
Current Employees apply HERE
Current Contingent Workers apply HERE
US and Puerto Rico Residents Only:
Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.
We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:
EEOC Know Your Rights
EEOC GINA Supplement
Pay Transparency Nondiscrimination
We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively.
Learn more about your rights, including under California, Colorado and other US State Acts
U.S. Hybrid Work Model
Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, generally Tuesday, Wednesday and either Monday or Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence. This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as "remote".
Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.
Employee Status:
Regular
Relocation:
Domestic
VISA Sponsorship:
No
Travel Requirements:
10%
Flexible Work Arrangements:
Not Applicable
Shift:
Not Indicated
Valid Driving License:
No
Hazardous Material(s):
N/A
Required Skills:
Chemistry, Computational Chemistry, Computer Aided Drug Design, Drug Design, High Performance Computing (HPC), Machine Learning, Molecular Dynamics (MD), Molecular Modeling, Problem Solving, Scientific Modeling, Structure Activity Relationship, Structure Based Drug Design, Teamwork
Preferred Skills:
Cheminformatics, Data Science, Informatics
Job Posting End Date:
09/22/2024
*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.
Job Posting End Date:09/22/2024
A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.
Requisition ID:R309450
Position Title
Principal Scientist, Computational Chemistry , West Point
Position Description
We are seeking a creative, self-motivated computational chemist with exceptional interpersonal and problem-solving skills to join the Modeling and Informatics team in West Point, PA, US .
M&I is a diverse and inclusive team of approximately 50 computational chemists and informaticians, who employ state of the art capabilities to drive drug design. We are an integral arm of both discovery and process chemistry and collaborate seamlessly with teams across the globe to innovate and invent better molecules faster . We are looking for a strategic thinker and accomplished computational drug hunter to take on a position that carries significant influence across our Company chemistry from target identification through delivery of clinical candidates in our Infectious Disease, Vaccine and Neuroscience portfolios .
Key responsibilities will include:
Scientific Innovation:
- Design and optimization of drug candidates using advanced computational techniques as a member of discovery teams
- Functioning as a subject matter champion for ligand - and structure - based drug design across discovery teams
- C ontributing to the continued growth and development of both modeling and chemistry colleagues as a mentor and influencer
- Advancing our modeling capabilities through invention and implementation of novel methodology as necessary to drive impact
Building Relationships:
- M entorship and scientific development of M&I staff both locally and across our network
- Building fruitful collaborations with stakeholders across medicinal chemistry, pharmacokinetics & pharmacodynamics, quantitative biosciences, and therapeutic area biology
- Trusted partner for Discovery Chemistry in West Point
- Identifying computational chemistry needs and opportunities across two broad portfolios for neuroscience and infectious disease at our West Point Chemistry hub in Pennsylvania.
Strategy:
- Leading specific strategic initiatives to enable our future vision for Modeling and Informatics in c hemistry
- Enabling a design-driven and predict-first culture throughout our Company Chemistry
- Contributing to our Company's overarching drug discovery strategy
We recognize that the diversity in our team is our strength and are committed to creating an inclusive environment for all employees. Successful candidates must demonstrate inclusive behaviors in working with a diverse group of scientists to drive our core mission.
Because we believe our best collaboration opportunities occur in a face-to-face context, this position will be in person, on site in West Point, PA.
Position Qualifications :
Education Minimum Requirement:
Ph.D. or M.S. degree in chemistry, biochemistry, biophysics, or equivalent with a computational emphasis .
Required Experience and Skills:
- 8 years of relevant professional experience ( i.e., Pharma, Biotech or equivalent) with a Ph.D., or 1 0 years with a M.S . degree.
- Proficiency in general molecular modeling techniques (docking, molecular simulation, homology modeling, quantum mechanics, QSAR / machine learning, ligand- and structure-based design) with modern software packages ( e.g. Schrodinger, OpenEye, CCG)
- Evidence of creative application of computational approaches to solve problems of pharmaceutical interest
- Exceptional oral and written communication skills, with a recognized ability to positively and impactfully influence team decisions
- Ability to communicate, collaborate and deliver results in a fast-paced, global environment and to manage multiple priorities simultaneously
- Ability to see the ' big picture ', and to identify opportunities for impact now and in the future
- Ability to lead strategic scientific initiatives relevant to drug discovery
- Passion for mentoring and coaching scientific peers
Preferred Experience and Skills:
- Skilled in scientific programming ( e.g. Python, Pipeline Pilot) and data analytics ( e.g. Spotfire) and democratizing coding and workflows
- People management experience
NOTICE FOR INTERNAL APPLICANTS
In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.
If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.
Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also with policies established by such external stakeholders (for example, a requirement to be vaccinated against COVID-19 in order to access a facility or meet with stakeholders). Please understand that, as permitted by applicable law, if you have not been vaccinated against COVID-19 and an essential function of your job is to call on external stakeholders who require vaccination to enter their premises or engage in face-to-face meetings, then your employment may pose an undue burden to business operations, in which case you may not be offered employment, or your employment could be terminated. Please also note that, where permitted by applicable law, the Company reserves the right to require COVID-19 vaccinations for positions, such as in Global Employee Health, where the Company determines in its discretion that the nature of the role presents an increased risk of disease transmission.
Current Employees apply HERE
Current Contingent Workers apply HERE
US and Puerto Rico Residents Only:
Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.
We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:
EEOC Know Your Rights
EEOC GINA Supplement
Pay Transparency Nondiscrimination
We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively.
Learn more about your rights, including under California, Colorado and other US State Acts
U.S. Hybrid Work Model
Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, generally Tuesday, Wednesday and either Monday or Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence. This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as "remote".
Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.
Employee Status:
Regular
Relocation:
Domestic
VISA Sponsorship:
No
Travel Requirements:
10%
Flexible Work Arrangements:
Not Applicable
Shift:
Not Indicated
Valid Driving License:
No
Hazardous Material(s):
N/A
Required Skills:
Chemistry, Computational Chemistry, Computer Aided Drug Design, Drug Design, High Performance Computing (HPC), Machine Learning, Molecular Dynamics (MD), Molecular Modeling, Problem Solving, Scientific Modeling, Structure Activity Relationship, Structure Based Drug Design, Teamwork
Preferred Skills:
Cheminformatics, Data Science, Informatics
Job Posting End Date:
09/22/2024
*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.
Job Posting End Date:09/22/2024
A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.
Requisition ID:R309450
Employers have access to artificial intelligence language tools (“AI”) that help generate and enhance job descriptions and AI may have been used to create this description. The position description has been reviewed for accuracy and Dice believes it to correctly reflect the job opportunity.
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