Scientist, Bioanalytical Chemistry

What’s in it for you?

In this role, you will be joining a growing organization working on cutting edge ADC technologies that present various interesting bioanalytical challenges. You will have the opportunity to develop, troubleshoot, innovate and qualify analytical methods to determine exposure-response profiles of antibody-drug conjugates using preclinical biological samples. You will work closely with management and project representatives to ensure alignment and manage timelines.   

There will be ample opportunity for innovation by implementing new analytical methods and learning new techniques. You will have the opportunity to work with mass spectrometry experts on ADC quantification and get trained on novel platforms.   As one of the scientists on the bioanalytical team, your decisions will influence the analytical strategies that we pursue. As the team continues to grow, there will be opportunities to develop leadership skills and hire, mentor and train junior scientists. This largely will be a laboratory-based role, but you also will be able to leverage your excellent communication, problem-solving and organizational skills as a bioanalytical representative on platform technology and pipeline project teams. You will possess the ability to self-organize and operate effectively without significant day-to-day oversight, while staying tightly connected to key leaders and teams across the company.   Your great results and insights will drive decision-making and help Mersana to advance new ADCs toward lead candidate status and ultimately, expand its clinical pipeline, and you are encouraged to publish your novel methods and present results at relevant conferences.
 

How do you know if you’re the right fit?

You are a PhD in life sciences or chemistry with emphasis on bioanalytical assays of biological products and/or biomarkers, immunology, multiplex technologies with 1-3 years of relevant pharmaceutical or biotech industrial experience.

Your experience includes analytical method development for large molecules and separation science and instrumental quantification methodologies. Hands on experience in ELISA, MSD and LC/MS are desired.  And this will set you up to make immediate contributions to the Bioanalytical team.  Experience with drug metabolism, high resolution mass spectrometry, automation is preferred but not required. You have created new bioanalytical methods for PK/biomarkers for large molecule. You have provided scientific input for in-house activities and outsourced work at CROs and have experience trouble-shooting assay related scientific issues at various stages of pharmaceutical development. You must also possess a proven track record of scientific expertise through publication and/or presentation.

 Your experience following analytical procedures and validation protocols with GLP and GMP compliance, maintaining accurate laboratory records and notebooks and writing analytical reports and SOPs will ensure your success.  You will also be eager to engage your colleagues inside and outside of the Clinical Pharmacology Department. Primarily, you are highly self-motivated, love doing great science and developing innovative technologies in an extensively collaborative environment. Excellent verbal and written communication skills are essential.

The other stuff

This is typically a role best suited for PhD-level candidates with degrees in immunology, biochemistry, chemistry, molecular biology, biotechnology, or related field related disciplines who possess 1-3 years of post-doctoral experience, preferably in the pharmaceutical/biotechnology industries or CROs. Candidates with M.S. degrees and 7 years of similar experience will be considered.  Hands on experience with in-depth knowledge of bioanalytical method development and a desire to continue this work is required. Occasional travel to CRO is required. This role will report to the Fellow of Analytical Chemistry.  

Position is eligible for bonus, option awards and benefits including medical, dental and life insurance and pet insurance, 401(k) participation, vacation, and paid holidays.

The successful candidate must be authorized to work in the United States.

Mersana Therapeutics, Inc. is an equal opportunity employer.