Scientist

Summary:

Discovery Biotherapeutics is seeking a temporary, knowledgeable, self-motivated scientist to provide Antibody Drug Conjugate Bioconjugation and Chemistry support for the advancement of the ADC portfolio at company. The successful candidate must have strong chemistry and/or bioconjugation background as they will temporarily support discovery research and early process development activities for ongoing and new ADC projects.

Essential Duties and Responsibilities:

• Conduct hands-on laboratories studies to support ADCs and bioconjugates.
• Provides chemistry and bioconjugation expertise for state-of-the-art ADC technologies including linkers, payloads, novel conjugation methods, analytical assessments and testing and bring novel ideas to POC.
• Assist in chemical synthesis discussion, planning and execution.
• Critical scientific/technical data analysis, interpretation of experiments and report writing.
• Effectively communicate scientific concepts, findings, and interpretation to multi-disciplinary teams.
• Follows company intellectual property and compliance policies and practices.
• Complies with company health and safety policies and general laboratory practices.

Education:

• PhD in Chemistry or a closely related field and a minimum of three (3) years of related experience; or,
• MS/MA in Chemistry or a closely related field and a minimum of seven (7) years of related experience; or,
• BS/BA in Chemistry or a closely related field and a minimum of nine (9) years of related experience; or,
• Equivalent combination of education and experience.

Experience:

• Strong scientific understanding of chemistry, mechanism of action of cytotoxins and ADCs, and pharmacology studies in discovery of ADCs.
• Hands on laboratory experience in bioconjugate research including critical reagent generation, identification, and optimization of bioconjugates, material production, purification, analytics, and characterization.
• Experience in various aspects of small molecule chemical synthesis is preferred.
• Demonstrated drive for rigorous scientific excellence. Ability to think critically and creatively to identify and solve scientific problems.

Knowledge/Skills/Abilities:

• Knowledge of state of the art in different aspects of ADC research including conjugation technologies, linkers, and payloads.
• Working knowledge of bioconjugation platforms, applications, and development.
• Good working knowledge in analytical techniques including NMR, HPLC, and LCMS.
• Ability to work independently, excellent time management and organization skills to manage multiple projects simultaneously.
• Excellent written, oral, and interpersonal communication skills.
• A strong team player.
• Good tracking record and report writing.

Job Complexity:

• Works on extremely complex problems where analysis of situations or data requires an evaluation of intangible variables.
• Exercises independent judgment in developing methods, techniques, and evaluation criteria for obtaining results.
• Uses professional concepts in accordance with company objectives to solve complex problems in creative and effective ways.