Scientist I, Analytical Development, Cell Therapy

Resilience is seeking a talented Scientist I to join our cell therapy analytical development team. This team is responsible for the design, development, and implementation of assays to advance the company’s novel T cell therapy programs. The successful candidate will have a background in assay development, preferably in molecular and cellular immunology and immune oncology, while also possessing strong interpersonal skills and the ability to work collaboratively with other groups within the organization. Job Responsibilities Participate in method development, qualification, validation, and transfer activities for in-vitro potency assays Assist in optimization and troubleshooting of new methods to improve capabilities and throughput in the analytical development laboratory Train and mentor junior team members Assist in the technology transfer of analytical methods to other departments and support analytical method qualification and/or validation if needed Assist in routine maintenance and calibration of analytical equipment Perform and coordinate testing to support analytical development, manufacturing process development, process validations, and manufacturing investigations across functional groups Participate in writing protocols, reports, and analytical sections for regulatory submissions such as INDs and BLAs Provide technical support to QC laboratories and assist in investigations as needed Accurately capture data in a timely manner, maintaining detailed records in compliance with applicable cGMP, safety, and environmental requirements Assist in compiling data for review and discussion within the Cell Therapy team Utilize digital technology (LIMS/ELN) for recording lab activities Required Qualifications Experience with in-vitro potency assay development for cell & gene therapy products Knowledge of method robustness, DoE, method design and assay validation parameters Experience using mammalian cell culture techniques and common immunological methods (ELISA, cytokine assays, flow cytometry, etc.) Good organizational skills and the ability to multitask Excellent oral and written communication skills Strong analytical problem solving, planning and organizational skills A self-starter and team player who can balance the velocity of startup environment with the quality and rigor of a clinical regulatory environment The required level of technical and professional proficiency is generally gained through 5 or more years of relevant experience in industry and/or academic research and development labs. Preferred Qualifications Ph.D. in Biochemistry, immunology, virology, biological science, or related discipline Prior experience in RNA/DNA isolation and molecular biology assays (qPCR, ddPCR, qRT-PCR) and related analytical software Experience with analytical or statistical software, e.g., Flowjo, Softmax Pro, GraphPad Prism Working knowledge of cGMP Quality systems Experience working with multiple virus families and/or multiple viral vectors Experience as a people manager of direct reports Resilience offers employees a robust total rewards program including equity, an annual cash bonus program, a 401(k) plan with a generous company match and our benefits package which is thoughtfully designed to support our employees with great healthcare (including medical, dental and vision), family building benefits, life and disability insurance, flexible time off, paid holidays, other paid leaves of absence, tuition reimbursement and support for caregiving needs. Our target annualized base pay hiring range for this position is $90,000.00 - $116,250.00. Actual base pay is dependent upon a number of factors, including but not limited to, the candidate’s geographical location, relevant experience, qualifications, skills and knowledge. Excited about Resilience and the biomanufacturing revolution? We encourage you to apply and start a conversation with one of our recruiters. RESILIENCE is a first-of-its-kind manufacturing and technology company dedicated to broadening access to complex medicines and protecting biopharmaceutical supply chains against disruption. Founded in 2020, the company is building a sustainable network of high-tech, end-to-end manufacturing solutions to ensure the medicines of today and tomorrow can be made quickly, safely, and at scale. RESILIENCE will offer the highest quality and regulatory capabilities, and flexible and adaptive facilities to serve partners of all sizes. By continuously advancing the science of biopharmaceutical manufacturing and development, RESILIENCE frees partners to focus on the discoveries that improve patients’ lives. Please Note – Resilience does not accept unsolicited agency resumes. Resilience will not pay any third-party agency or company that does not have a signed agreement with Resilience. Culture Focus Sites

Salary : $90,000 - $0