Senior Scientist

Senior Scientist

73 Bioanalytical

Full Time (Full-Time)

PharmOptima, Portage (Kalamazoo), Michigan US

PharmOptima, a member of Genesis Biotechnology Group and Genesis Global Group, is a fully integrated contract research organization (CRO) providing services to support preclinical drug and discovery programs from early discovery through clinical development. PharmOptima focuses on ADME/PK, Bioanalysis, and Biochemistry research services within the biotechnology and pharmaceutical industries. We celebrate 25 years of innovation, teamwork, growth and success.  

Job Description:

PharmOptima is seeking an enthusiastic colleague to fill a challenging and fast-paced senior scientist position in our Bioanalytical group located in Portage, Michigan. Join the bioanalytical team committed to support innovative biological drug discovery efforts and make a difference in lives.

Responsibilities include, but are not limited to: 

• Develop, optimize, and validate LC-MS/MS bioanalytical methods within biological matrices with high technical level report writing upon completion of study
• Develop and implement assays for bioanalysis of small molecules, peptides, and amino acids in both a non-GLP regulated and GLP regulated environment 
• Perform instrumentation qualifications, calibrations, and verifications 
• Use and maintenance of Sciex (Analyst® Software) and Thermo Scientific (Xcalibur® software) triple quadrupole mass spectrometers
• Experience in PK study design, data interpretation, and analysis

Minimum Qualifications:

• A M.S. degree in chemistry, biology, or biochemistry and 2 years of relevant industry experience or a Ph.D. in chemistry, biology, or biochemistry
• Experience developing, executing, and troubleshooting LC-MS/MS assays and methods
• Experience with sample extraction techniques such as PPT, SLE, and Derivatization
• Excellent written and oral communication skills
• Time management, organizational skills, and a high level of attention to detail 
• Ability to work effectively as both an individual contributor and in a collaborative team setting.
• Knowledge regarding troubleshooting techniques of bioanalytical assay development, qualification, validation, and sample analysis
• Experience in the application of Good Laboratory Practices (GLP) to provide accurate documentation of analytical results