Research Technician

Xyzagen
Pittsboro, NC Full Time
POSTED ON 12/10/2024
AVAILABLE BEFORE 2/10/2025

We are seeking bright, highly motivated, and organized individuals who are interested in joining a dynamic, intellectually challenging, and growing organization. Successful candidates will be optimistic, solutions-oriented, accountable, and open-minded with a positive, can-do attitude and a strong ability to solve problems.

Xyzagen (Zi*Za*Gen) is a contract research lab supporting in vivo pharmacokinetics, in vitro ADME, small and large molecule bioanalysis, ophthalmology and neurology pharmacology and nonGLP safety assessments in mice and rats. Xyzagen is also a drug development consultancy providing regulatory advice to clients in the nonclinical and clinical pharmacokinetic disciplines, IND and NDA submissions. Xyzagen has provided strategic advice to early NIH funded biotechs, small and mid-size pharma and venture capital firms. At Xyzagen, we accelerate medicines to patients by partnering with life science innovators. In the past 6 years, we have worked with over 100 different innovators and have helped in the approval of multiple new therapeutics by the FDA.

The Research Technician will: 

  • Maintain the laboratory and vivarium by 
    • Ensuring organization of supplies, requestion of supplies and that solvents, solutions are maintained and glassware is clean.
    • Being responsible for animal husbandry and maintaining the vivarium and participating in study design, investigation, data collection and tabulation for client studies
    • Maintaining cold-storage inventory of materials and samples
  • Conduct animal dosing experiments and perform sample and tissue collections 
  • Contribute to the expansion of models and in vivo pharmacology testing
  • Provide general and molecular biology expertise to the laboratory for in vitro studies
  • Work with senior scientific staff on ELISA and/or mass spectrometry based bioanalytical methods
  • Conduct additional in vitro work as needed for client or internal research projects
  • Summarize experimental procedures and results into written documentation
Individuals who will be successful in this role will be self-motivated and able to function independently after training. This is a full-time position with an occasional need to work weekends. The weekend work will be minimal, but the flexibility to work weekends is required. Additionally, strong time management skills are required to balance scientific work and any client associated projects (70/30 split).  
 

Job Requirements
Education & Experience:

  • Associate degree or BS in a scientific field or related discipline with 1 year of relevant experience
  • At least 1 year of academic or industrial experience with laboratory rodents, including mouse husbandry/colony management 
  • Experience with technical skills such as intravenous route (tail vein or other routes) of administration and blood collection in rodents
  • Have AALAS certification (ALAT, LAT, LATG) or an interest in becoming certified

Qualifications: Key skills/desired experience

  • Hands-on experience with laboratory rodents, including mouse and rat husbandry/colony management 
  • Experience maintaining a vivarium 
  • Expertise with drug administration to rodents via various routes of administration (including tail vein)
  • Understanding of sterile environment preparation, proper use of PPE, and be able to collect tissues and handle biological materials
  • In-lab technical experience such as molecular biology assays (ELISA), chemical assays (HPLC, mass spectrometry) and/or necropsy/histology techniques  
  • Ability to understand and follow the Institutional Animal Care and Use Committee (IACUC) guidelines and policies and study-specific protocols 
  • Moderate technical writing and scientific skills for making accurate assumptions from limited data and to propose the next possible step 
  • General understanding of basic laboratory techniques
  • Demonstrated experience effectively managing multiple projects with a strong attention to detail
  • Ability to work independently but also collaborate as a team player
  • Strong verbal and written communication skills to internal and external audiences
  • Understanding and experience using computers and software is preferred (e.g. Microsoft Office, Graph Pad Prism) 

Physical Requirements: 
The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this position. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. 

  • While performing the duties of this Job, the employee is frequently required to sit or stand for extended periods of time; use fine and gross motor hand skills in ensuring analytical equipment is maintained in operation.
  • The employee must be able to speak and hear appropriately to communicate effectively with each associate or vendor.
  • This role requires individuals to wear PPE when applicable.
  • The employee is regularly required to stand, walk, twist the torso, bend over and reach with hands and arms. The employee on occasion will be required to lift and/or move up to 40 pounds.
  • Specific vision abilities required by this job include close, distance and peripheral vision with the ability to adjust and focus.

Working Conditions:

  • While performing the duties of this job, the employee is frequently exposed to moving mechanical parts and fumes or airborne particles; toxic or caustic chemicals; blood borne pathogens (i.e., urine, feces, blood, instruments, and sharps); dust and extremely hot water; and laboratory equipment.
  • The noise level in the work environment is usually mild to moderate.

Benefits
What We Offer: 

  • A competitive salary and meaningful equity compensation
  • The compensation for this position will range from $40,000 to $50,000 depending on individual’s qualifications. 
  • A bright, collegial, highly motivated team working at the intersection of the most exciting area of science and technology
  • Exceptional opportunities for learning and growth
  • Company-paid holidays (closed between Christmas and New Year’s)
  • Paid time off (2 weeks)
  • Health benefit stipend
  • 401(k) plan Safe Harbor Match Profit Sharing Defined Benefit retirement plan
  • Flexible time off for personal business is not tracked 
  • Ability to work from home when possible
  • Flexible schedule

Xyzagen is committed to the health and safety of employees and requires all employees be 100% vaccinated prior to starting employment unless they are granted a medical or religious exemption.

Xyzagen is a small company such that we are unable to sponsor visas for any candidate who is not eligible to work in the United States. Additionally, we cannot assist with the transfer of an employment visa from another company.

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