10x Genomics, Inc. Computational Biologist - Products & Applications Salary in the United States

Computational Biologist: Products & Applications

At 10x Genomics, accelerating our understanding of biology is more than a mission for us. It’s a commitment. This is the century of biology, and the breakthroughs we make now have the potential to change the world.
We enable scientists to advance their research, allowing them to address scientific questions they didn’t even know they could ask. Our tools have enabled fundamental discoveries described in over 1000 peer-reviewed publications across multiple application areas, including cancer, immunology, and neuroscience.  

Our teams are empowered and encouraged to follow their passions, pursue new ideas, and perform at their best in an inclusive and dynamic environment. The innovations and discoveries that we enable together will lead to better technologies, better treatments, and a better future. Find out how you can make a 10x difference!

About the role:
 
We are looking for an outstanding individual to join our Computational Biology group. You will work closely with talented biochemists, microfluidics engineers, chemists and software engineers to analyze data generated from our single-cell and spatial genomic assays. Our products have allowed researchers to study biology at unprecedented resolution and scale, yielding insights in diverse fields such as cancer biology, immunology, neuroscience, developmental and basic biology.
You will develop analyses to measure, improve, and optimize product performance during a fast-paced product development cycle. This includes discovering issues through careful analysis of sequencing data and working collaboratively with the interdisciplinary product team to help resolve them. Working with our R&D group and with external partners you will solve problems by developing insights into high-resolution and high-throughput biological data. 

You will also contribute to the development of our software tools so that all our users can benefit from your abilities to extract information from the data generated by our assays. 
You have a strong background in computational biology or bioinformatics and you have experience working with single cell data. You have a deep understanding of biology at the cellular and molecular level and can interpret the results of your analyses within their biological context. You are a strong programmer who can take an idea and quickly implement it in code. You are able to communicate your ideas and work effectively with an interdisciplinary team and incorporate their feedback into your analysis. You are a strategic thinker, highly motivated, proactive and flexible in changing direction and methods. You thrive in a fast paced environment, excel at managing multiple priorities, communicate clearly and get the job done.
 
What you will be doing:

- Using existing and novel computational approaches to analyze complex single cell and spatial datasets
- Using exploratory analysis and statistical models to troubleshoot and optimize sample prep and assay methods
- Working with internal groups at 10x as well as external partners to solve problems with data analysis
- Defining experimental metrics for measuring assay quality, and determine goals & priorities for assay development work.
Contribute to 10x software tools

To be successful in this role, You will need:

- PhD or MS plus equivalent experience in a quantitative field (e.g. biology, bioinformatics, computational/systems biology, physics, mathematics, computer science)
- Experience working on problems involving complex biological systems at high-resolution
- Experience using computational methods to extract insight from large datasets
- Experience with the analysis of NGS data
- Strong grounding in the state-of-the art with respect to single cell biology and computational analysis
- Ability to quickly conceive and implement custom computational methods and algorithms and apply them to large data sets.
- Strong programming ability in a language such as Python or R
- Ability to work in a fast-paced and quickly changing environment
- Ability to communicate complex ideas with an interdisciplinary team
- Ability to work independently

Additional desirable skills to have:

- Creative problem solver who obsesses over finding useful biologically relevant information in data
- Experience working in an applied biological field such as immunology, tumor biology, neurobiology or similar

All qualified applicants will receive consideration for employment without regard to race, sex, color, religion, sexual orientation, gender identity, national origin, protected veteran status, or on the basis of disability.