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Clinical Database Manager Salary in the United States

How much does a Clinical Database Manager make in the United States?

As of September 01, 2026, the average salary for a Clinical Database Manager in the United States is $144,700 per year, which breaks down to an hourly rate of $70.

However, a Clinical Database Manager's salary can vary significantly. Here’s a look at the typical salary range:

  • Top Earners (90th percentile): $180,807
  • Majority Range (25th-75th percentile): $133,000 to $163,600
  • Entry-Level (10th percentile): $122,348
Salary Factors Salary-Boosting Skills Salary by Experience Related Job Salaries Top Paying Cities Explore Related Jobs

Key Factors That Influence Clinical Database Manager Salaries

A Clinical Database Manager's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location, education and company size can directly affect your earning potential.

How Experience Level Affects Clinical Database Manager Salaries?

Experience is a primary driver of a Clinical Database Manager's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here's how the average salary grows at different career stages:

  • Entry-Level (less than 1 year): $140,334
  • Early Career (1-2 years): $140,858
  • Mid-Level (2-4 years): $144,700
  • Senior-Level (5-8 years): $150,906
  • Expert (over 8 years): $151,752
Levels Salary
Entry Level Clinical Database Manager$140,334
Intermediate Level Clinical Database Manager$140,858
Senior Level Clinical Database Manager$144,700
Specialist Level Clinical Database Manager$150,906
Expert Level Clinical Database Manager$151,752
View as Graph

How Do Clinical Database Manager Salaries Vary from State to State?

Your salary can change significantly depending on where you work. States with a higher cost of living and strong industrial sectors often pay more to attract Clinical Database Managers. For example, consider the average annual salaries in these key locations:
  • District of Columbia: $160,200.
  • California: $159,600.
  • Massachusetts: $157,400.

Top Paying Cities for Clinical Database Managers

Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:

  • San Jose: $182,500
  • San Francisco: $180,500
  • Oakland: $176,700

What Skills Can Increase a Clinical Database Manager's Salary?

Demanded Skills for the Role:

  • Project Management (Mentioned in 2.56% Job Postings): Project management is the application of processes, methods, skills, knowledge and experience to achieve specific project objectives according to the project acceptance criteria within agreed parameters. Project management has final deliverables that are constrained to a finite timescale and budget.
  • Database Design (Mentioned in 2.07% Job Postings): Overlap to row 560
  • Data Collection (Mentioned in 1.59% Job Postings): Data collection is the process of gathering and measuring information on targeted variables in an established system, which then enables one to answer relevant questions and evaluate outcomes. Data collection is a component of research in all fields of study including physical and social sciences, humanities, and business. While methods vary by discipline, the emphasis on ensuring accurate and honest collection remains the same. The goal for all data collection is to capture quality evidence that allows analysis to lead to the formulation of convincing and credible answers to the questions that have been posed.
Skills Demand Percentage
Project Management 2.56%
Database Design 2.07%
Data Collection 1.59%
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What skills can make your compensation higher?

Mastering certain specialized skills can lead to a significant increase in pay. Here are examples of skills and the potential impact they can have on a Clinical Database Manager's salary.

  • Biostatistics: Can increase your salary by up to 5%.
  • Drug Development: Can increase your salary by up to 5%.
  • Programming: Can increase your salary by up to 4%.
Skill Salary Salary % Increase
Biostatistics $151,935
5%
Drug Development $151,935
5%
Programming $150,488
4%
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Clinical Database Manager Salary by Company Size: Startups vs. Enterprise

Clinical Database Manager salary potential scales significantly with company size. Data shows that Enterprise companies (5,000+ employees) pay the highest average salary at around $161,334. While startup companies pay approximate $136,937.

Clinical Database Manager Salary by Company Size

Company Size Employees Average Salary
Startup 1~50 $136,937
Growth Stage 51~500 $144,706
Established 501~5000 $155,902
Enterprise 5000+ $161,334

Clinical Database Manager Salary by Industry: Top Paying Sectors

For Clinical Database Manager roles, the industry you choose can affect earning potential by as much as 40% (the gap between the highest and lowest paying industries). Data shows that the Biotechnology and Edu., Gov't. & Nonprofit sectors offer the strongest compensation, at 20% above the average. In contrast, Clinical Database Manager positions in Business Services or Healthcare typically offer lower base pay, as these industries often view Clinical Database Manager as a support function rather than a direct revenue driver.

The top paying industries for a Clinical Database Manager

Industry Sector Average Annual Salary Average Hourly Rate Pay vs.Avg
Biotechnology$173,640$83.020%
Edu., Gov't. & Nonprofit$159,170$77.010%

How Education impacts a Clinical Database Manager's Salary?

Your level of education can impact your salary potential. While many Clinical Database Managers enter the field with a Master's Degree or MBA degree, higher education can lead to more specialized and higher-paying roles.

According to our 100% employer-reported salary data, the median salary for a Clinical Database Manager with a Master's Degree or MBA is between $118,787 and $125,210).

Clinical Database Manager Salaries by Degree Level

Typical Education for Clinical Database Manager
Degree Level % of user with this level of education
No Diploma 7.3%
High School 7.3%
Associates 2.9%
Bachelors 49.6%
Masters 32.8%
Doctorate 7.3%
View as Graph

Clinical Database Manager Salary: Hourly Rate, Weekly Pay, and Monthly Pay

Understanding how a Clinical Database Manager's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.

Last Updated on September 01, 2026
$133,000
Average $144,700/year
$163,600
$11,083
Average $12,058/month
$13,633
$2,558
Average $2,783/week
$3,146
$64
Average $70/hour
$79
Annual Salary Monthly Pay Weekly Pay Hourly Wage
75th Percentile $163,600 $13,633 $3,146 $79
Average $144,700 $12,058 $2,783 $70
25th Percentile $133,000 $11,083 $2,558 $64

Most common benefits for Clinical Database Manager

  • Social Security
  • 401 (k)
  • Disability
  • Healthcare
  • Pension
  • Time Off (days)

Common company salaries for Clinical Database Manager

Here are companies hiring for Clinical Database Manager and their salaries, click below for more details.

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FAQ about Clinical Database Manager

1. What industry pays the highest salary for Clinical Database Manager?

The Biotechnology industry offers the highest average compensation for Clinical Database Manager roles, with salaries approximately 20% above the market median.

2. What is the highest salary for a clinical data manager?

The highest salary for a Clinical Database Manager is approximately $136,600 per year. The average salary typically ranges from $112,600 to $123,500, depending on experience and qualifications. This reflects the competitive nature of the role in the healthcare and clinical research sectors.

3. How much do clinical managers make in the US?

As of now, Clinical Database Managers in the United States earn between $112,600 and $136,600 annually, with a median salary of $123,500. This translates to approximately $54.05 to $65.69 per hour, or $2,304 to $2,854 per week. The monthly earnings range from $9,383 to $11,800, reflecting the specialized nature of this role.

4. What type of manager pays the most?

The highest-paid manager roles include Clinical Database Manager, with a salary range from $112,600 to $136,600, offering a mid-salary of $123,500. Other high-paying positions are Store Manager, Farm Manager, and Marketing Manager, among others. These roles typically command competitive salaries based on industry and responsibilities.

5. What is the highest salary in clinical data management?

The highest salary for a Clinical Database Manager is $136,600. The top 10% of professionals in this field earn more than $123,500, while the top 1% can exceed $112,600. This reflects the competitive nature of clinical data management and the value placed on skilled professionals in the industry.

6. What is the job outlook for a clinical data manager?

The job outlook for Clinical Data Managers shows a significant increase in vacancies, rising by 93.70 percent nationwide. However, demand is projected to decline, with an expected loss of 16,280 jobs by 2029, translating to an annual decrease of 3.03 percent. Salaries for this role range from $112,600 to $136,600, with a median salary of $123,500.

7. What is the highest salary in clinical data management?

The highest salary offered for a Clinical Database Manager is $136,600. This reflects the top end of the salary range for professionals in clinical data management, with a minimum salary of $112,600 and a mid-range salary of $123,500.

Where Does Our Salary Data Come From?

Salary.com provides salary estimates, histograms, trends, and comparisons using data from employer job postings and third-party sources.

We offer detailed salary information across multiple percentiles for your reference. (Click here to learn Why the Salary Midpoint Formula Is Crucial for Achieving Pay Equity.)

With the most extensive online, real-time compensation data available, Salary.com helps you pinpoint your exact pay target.

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