Salary AI Book a Demo

Head of Clinical Information Systems Salary in the United States

How much does a Head of Clinical Information Systems make in the United States?

As of October 01, 2026, the average salary for a Head of Clinical Information Systems in the United States is $361,570 per year, which breaks down to an hourly rate of $174.

However, a Head of Clinical Information Systems's salary can vary significantly. Here’s a look at the typical salary range:

  • Top Earners (90th percentile): $385,240
  • Majority Range (25th-75th percentile): $341,920 to $373,960
  • Entry-Level (10th percentile): $324,030
Salary Factors Salary-Boosting Skills Salary by Experience Related Job Salaries Top Paying Cities Explore Related Jobs

Key Factors That Influence Head of Clinical Information Systems Salaries

A Head of Clinical Information Systems's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location, education and company size can directly affect your earning potential.

How Experience Level Affects Head of Clinical Information Systems Salaries?

Experience is a primary driver of a Head of Clinical Information Systems's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here's how the average salary grows at different career stages:

  • Clinical Information Systems Manager (7+ years): $139,150
  • Clinical Information Systems Senior Manager (7+ years): $155,918
  • Clinical Information Systems Director (7+ years): $172,572
  • Chief Nursing Information Officer (CNIO) (7+ years): $223,960
  • Head of Clinical Information Systems (7+ years): $361,570
Job Role Years of Experience Average Salary
Clinical Information Systems Manager7+ years$139,150
Clinical Information Systems Senior Manager7+ years$155,918
Clinical Information Systems Director7+ years$172,572
Chief Nursing Information Officer (CNIO)7+ years$223,960
Head of Clinical Information Systems7+ years$361,570
View as Graph

How Do Head of Clinical Information Systems Salaries Vary from State to State?

Your salary can change significantly depending on where you work. States with a higher cost of living and strong industrial sectors often pay more to attract Head of Clinical Information Systems. For example, consider the average annual salaries in these key locations:
  • District of Columbia: $400,340.
  • California: $398,820.
  • Massachusetts: $393,500.

Top Paying Cities for Head of Clinical Information Systems

Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:

  • San Jose: $456,050
  • San Francisco: $451,060
  • Oakland: $441,550

What Skills Can Increase a Head of Clinical Information Systems's Salary?

Demanded Skills for the Role:

  • Leadership (Mentioned in 16.3% Job Postings): Knowledge of and ability to employ effective strategies that motivate and guide other members within our business to achieve optimum results.
  • Patient Care (Mentioned in 3.26% Job Postings): Patient care refers to the prevention, treatment, and management of illness and the preservation of physical and mental well-being through services offered by health professionals.
  • Managed Care (Mentioned in 2.17% Job Postings): Managed Care is a health care delivery system organized to manage cost, utilization, and quality. Also known as managed healthcare.
Skills Demand Percentage
Leadership 16.3%
Patient Care 3.26%
Managed Care 2.17%
See More Skills

What skills can make your compensation higher?

Mastering certain specialized skills can lead to a significant increase in pay. Here are examples of skills and the potential impact they can have on a Head of Clinical Information Systems's salary.

  • Clinical Care: Can increase your salary by up to 21%.
  • Empathy: Can increase your salary by up to 21%.
  • Grant Writing: Can increase your salary by up to 19%.
Skill Salary Salary % Increase
Clinical Care $437,500
21%
Empathy $437,500
21%
Grant Writing $430,268
19%
Get Latest Data

Head of Clinical Information Systems Salary by Company Size: Startups vs. Enterprise

Head of Clinical Information Systems salary potential scales significantly with company size. Data shows that Enterprise companies (5,000+ employees) pay the highest average salary at around $402,539. While startup companies pay approximate $341,541.

Head of Clinical Information Systems Salary by Company Size

Company Size Employees Average Salary
Startup 1~50 $341,541
Growth Stage 51~500 $360,988
Established 501~5000 $388,826
Enterprise 5000+ $402,539

Head of Clinical Information Systems Salary by Industry: Top Paying Sectors

For Head of Clinical Information Systems roles, the industry you choose can affect earning potential by as much as 90% (the gap between the highest and lowest paying industries). Data shows that the Healthcare and Business Services sectors offer the strongest compensation, at 50% above the average. In contrast, Head of Clinical Information Systems positions in Insurance or Biotechnology typically offer lower base pay, as these industries often view Head of Clinical Information Systems as a support function rather than a direct revenue driver.

The top paying industries for a Head of Clinical Information Systems

Industry Sector Average Annual Salary Average Hourly Rate Pay vs.Avg
Healthcare$542,355$261.050%
Business Services$433,884$209.020%

How Education impacts a Head of Clinical Information Systems's Salary?

Your level of education can impact your salary potential. While many Head of Clinical Information Systems enter the field with a No Diploma degree, higher education can lead to more specialized and higher-paying roles.

According to our 100% employer-reported salary data, the median salary for a Head of Clinical Information Systems with a No Diploma is between $322,223 and $359,482).

Head of Clinical Information Systems Salaries by Degree Level

Typical Education for Head of Clinical Information Systems
Degree Level % of user with this level of education
No Diploma 20.0%
High School 20.0%
Associates 20.0%
Bachelors 20.0%
Masters 60.0%
Doctorate 0.0%
View as Graph

Head of Clinical Information Systems Salary: Hourly Rate, Weekly Pay, and Monthly Pay

Understanding how a Head of Clinical Information Systems's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.

Last Updated on October 01, 2026
$341,920
Average $361,570/year
$373,960
$28,493
Average $30,131/month
$31,163
$6,575
Average $6,953/week
$7,192
$164
Average $174/hour
$180
Annual Salary Monthly Pay Weekly Pay Hourly Wage
75th Percentile $373,960 $31,163 $7,192 $180
Average $361,570 $30,131 $6,953 $174
25th Percentile $341,920 $28,493 $6,575 $164

Most common benefits for Head of Clinical Information Systems

  • Social Security
  • 401 (k)
  • Disability
  • Healthcare
  • Pension
  • Time Off (days)

Common company salaries for Head of Clinical Information Systems

Here are companies hiring for Head of Clinical Information Systems and their salaries, click below for more details.

Find Your Next Head of Clinical Information Systems Job

Ready to take the next step in your career? Browse thousands of current Head of Clinical Information Systems job openings on our job board. Use the search bar below to find your perfect match.

For Employees

Analyze the market and your qualifications to negotiate your salary with confidence.

Get a Salary Increase

Search thousands of open positions to find your next opportunity.

Search Job Openings

For Employers

Individualize employee pay based on unique job requirements and personal qualifications.

Adjust Employee Salary

Get the latest market price for benchmark jobs and jobs in your industry.

Price My Industry Jobs

FAQ about Head of Clinical Information Systems

1. What industry pays the highest salary for Head of Clinical Information Systems?

The Healthcare industry offers the highest average compensation for Head of Clinical Information Systems roles, with salaries approximately 50% above the market median.

2. How much does a head of IT make in the US?

The estimated total pay for a Head of Clinical Information Systems in the US ranges from $319,240 to $434,940 per year, with a mid-salary of $382,070. These figures reflect the salary range based on industry data and represent the midpoint of the compensation spectrum for this role.

3. What is the highest salary in management information systems?

The highest salary for a Head of Clinical Information Systems is $434,940, with a minimum salary of $319,240 and a mid-range salary of $382,070. This reflects a significant earning potential in the field, surpassing typical salaries in management information systems, which generally range from $80,000 to $138,500.

4. How much do clinical managers make in the US?

Clinical managers in the US earn varying salaries based on their experience and responsibilities. The salary range for a Head of Clinical Information Systems is between $319,240 and $434,940 annually, with a median salary of $382,070. This reflects the higher compensation levels for specialized roles in clinical management.

5. What is the highest salary in MIS?

The highest salary for the Head of Clinical Information Systems is ₹434,940, with a minimum salary of ₹319,240 and a mid-range salary of ₹382,070. This reflects the competitive compensation in the field, highlighting the value of expertise in clinical information management.

6. How much does a head of IT make in the US?

As of the latest data, the salary for a Head of Clinical Information Systems in the United States ranges from $319,240 to $434,940 annually, with a median salary of $382,070. This reflects the competitive compensation for this critical role in managing clinical information systems.

7. What degree do you need to be a clinical manager?

To become a clinical manager, you typically need a bachelor's degree in health administration or a related field from an accredited university. The salary for a Head of Clinical Information Systems ranges from $319,240 to $434,940, with a median salary of $382,070, reflecting the importance and responsibility of this role in healthcare management.

Where Does Our Salary Data Come From?

Salary.com provides salary estimates, histograms, trends, and comparisons using data from employer job postings and third-party sources.

We offer detailed salary information across multiple percentiles for your reference. (Click here to learn Why the Salary Midpoint Formula Is Crucial for Achieving Pay Equity.)

With the most extensive online, real-time compensation data available, Salary.com helps you pinpoint your exact pay target.

Are you an HR manager or compensation specialist?

Salary.com's CompAnalyst platform offers:

  • Detailed skills and competency reports for specific positions
  • Job and employee pricing reports
  • Compensation data tools, salary structures, surveys and benchmarks.
Learn about CompAnalyst
lower level job