Clinical Systems Engineer Salary in the United States

How much does a Clinical Systems Engineer make in the United States?

As of September 01, 2026, the average salary for a Clinical Systems Engineer in the United States is $110,955 per year, which breaks down to an hourly rate of $53.

However, a Clinical Systems Engineer's salary can vary significantly. Here’s a look at the typical salary range:

  • Top Earners (90th percentile): $121,180
  • Majority Range (25th-75th percentile): $101,621 to $116,307
  • Entry-Level (10th percentile): $93,123

Key Factors That Influence Clinical Systems Engineer Salaries

A Clinical Systems Engineer's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location, education and company size can directly affect your earning potential.

How Experience Level Affects Clinical Systems Engineer Salaries?

Experience is a primary driver of a Clinical Systems Engineer's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here's how the average salary grows at different career stages:

  • Entry-Level (less than 1 year): $62,072
  • Early Career (1-2 years): $76,874
  • Mid-Level (2-4 years): $111,603
  • Senior-Level (5-8 years): $135,579
  • Expert (over 8 years): $159,886
Levels Salary
Product/B... Level Clinical Systems Engineer$62,072
Product/B... Level Clinical Systems Engineer$76,874
Clinical ... Level Clinical Systems Engineer$111,603
Product/B... Level Clinical Systems Engineer$135,579
Product/B... Level Clinical Systems Engineer$159,886

How Do Clinical Systems Engineer Salaries Vary from State to State?

Your salary can change significantly depending on where you work. States with a higher cost of living and strong industrial sectors often pay more to attract Clinical Systems Engineers. For example, consider the average annual salaries in these key locations:
  • District of Columbia: $122,849.
  • California: $122,383.
  • Massachusetts: $120,752.

Top Paying Cities for Clinical Systems Engineers

Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:

  • San Jose: $139,948
  • San Francisco: $138,415
  • Oakland: $135,498

What Skills Can Increase a Clinical Systems Engineer's Salary?

Demanded Skills for the Role:

  • Analysis (Mentioned in 9% Job Postings): Analysis is the process of considering something carefully or using statistical methods in order to understand it or explain it.
  • Agile (Mentioned in 2.05% Job Postings): Agile is a development process where feedback is continuously gathered from users to create the best user experience.
  • BI (Mentioned in 1.38% Job Postings): Business intelligence (BI) is a technology-driven process for analyzing data and delivering actionable information that helps executives, managers and workers make informed business decisions.
Skills Demand Percentage
Analysis 9%
Agile 2.05%
BI 1.38%

What skills can make your compensation higher?

Mastering certain specialized skills can lead to a significant increase in pay. Here are examples of skills and the potential impact they can have on a Clinical Systems Engineer's salary.

  • B2C: Can increase your salary by up to 18%.
  • B2B: Can increase your salary by up to 13%.
  • Product Marketing: Can increase your salary by up to 12%.
Skill Salary Salary % Increase
B2C $130,927
18%
B2B $125,379
13%
Product Marketing $124,270
12%

Clinical Systems Engineer Salary by Industry: Top Paying Sectors

For Clinical Systems Engineer roles, the industry you choose can affect earning potential by as much as 80% (the gap between the highest and lowest paying industries). Data shows that the MFG Durable and Construction sectors offer the strongest compensation, at 40% above the average. In contrast, Clinical Systems Engineer positions in MFG Nondurable or Media typically offer lower base pay, as these industries often view Clinical Systems Engineer as a support function rather than a direct revenue driver.

The top paying industries for a Clinical Systems Engineer

Industry Sector Average Annual Salary Average Hourly Rate Pay vs.Avg
MFG Durable$155,337$75.040%
Construction$144,242$69.030%
Internet$138,694$67.025%
Aerospace & Defense$133,146$64.020%
Hospitality & Leisure$127,598$61.015%

How Education impacts a Clinical Systems Engineer's Salary?

Your level of education can impact your salary potential. While many Clinical Systems Engineers enter the field with a Associate's Degree degree, higher education can lead to more specialized and higher-paying roles.

According to our 100% employer-reported salary data, the median salary for a Clinical Systems Engineer with a Associate's Degree is between $103,197 and $109,888).

Clinical Systems Engineer Salaries by Degree Level

Typical Education for Clinical Systems Engineer
Degree Level % of user with this level of education
No Diploma 4.9%
High School 4.9%
Associates 58.2%
Bachelors 36.1%
Masters 58.2%
Doctorate 0.8%

Clinical Systems Engineer Salary: Hourly Rate, Weekly Pay, and Monthly Pay

Understanding how a Clinical Systems Engineer's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.

Last Updated on September 01, 2026
$101,621
Average $110,955/year
$116,307
$8,468
Average $9,246/month
$9,692
$1,954
Average $2,134/week
$2,237
$49
Average $53/hour
$56
Annual Salary Monthly Pay Weekly Pay Hourly Wage
75th Percentile $116,307 $9,692 $2,237 $56
Average $110,955 $9,246 $2,134 $53
25th Percentile $101,621 $8,468 $1,954 $49

Most common benefits for Clinical Systems Engineer

  • Social Security
  • 401 (k)
  • Disability
  • Healthcare
  • Pension
  • Time Off (days)

Common company salaries for Clinical Systems Engineer

Here are companies hiring for Clinical Systems Engineer and their salaries, click below for more details.

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FAQ about Clinical Systems Engineer

1. What industry pays the highest salary for Clinical Systems Engineer?

The MFG Durable industry offers the highest average compensation for Clinical Systems Engineer roles, with salaries approximately 40% above the market median.

Where Does Our Salary Data Come From?

Salary.com provides salary estimates, histograms, trends, and comparisons using data from employer job postings and third-party sources.

We offer detailed salary information across multiple percentiles for your reference. (Click here to learn Why the Salary Midpoint Formula Is Crucial for Achieving Pay Equity.)

With the most extensive online, real-time compensation data available, Salary.com helps you pinpoint your exact pay target.

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