As of February 01, 2026, the average annual salary for Machine Learning Engineer in Saint Louis, MO is $106,220, equivalent to $51 per hour, $2,043 weekly, or $8,852 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for Machine Learning Engineer in cities like Santa Clara, San Jose, and Fremont.
Annually Salaries for Machine Learning Engineer in Saint Louis, MO vary widely, spanning from $90,063 to $123,484. Most professionals fall between the 25th percentile ($97,763) and 75th percentile ($115,257), while top earners (90th percentile) make $123,484 per year. This $17,494 pay gap underscores opportunities for salary growth through certifications, specialized skills like Analysis or Software Development, or targeting high-paying regions like District of Columbia or California.
Location and experience significantly influence earnings. For example, Saint Louis Machine Learning Engineer often earn 1.7% lower than national averages. However, Saint Louis currently ranks 497 statewide for Machine Learning Engineer job salary. Professionals are advised to focus on high-growth sectors like to offset market challenges.