Yes, registered nurses can earn $50 an hour, especially in states with higher average salaries. For example, in Hawaii, the average RN salary is approximately $104,830 annually, which translates to about $50.40 per hour, making it feasible for nurses to earn at least $50 per hour in that state. Similarly, in California, the average salary is around $120,560 annually, equating to roughly $57.96 per hour. These figures demonstrate that in certain regions with higher demand and cost of living, nurses can comfortably earn $50 or more per hour. However, wages vary depending on location, experience, and healthcare facility, so not all nurses may reach this rate universally.