The difference between a probability sample and a non-probability sample lies in the method of selection. A probability sample involves a random selection process, giving each subject an equal chance of being chosen. This method aims to create a sample that accurately represents the population, allowing for generalizable results. On the other hand, a non-probability sample does not involve random selection, instead, subjects are chosen based on specific characteristics or belonging to a particular group. This method aims to draw conclusions about a specific group or subjects with similar factors. Probability sampling is commonly used in quantitative research for statistical accuracy, while non-probability sampling is often used in qualitative research to generate new ideas and hypotheses.