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Clinical Study Project Management Manager, Sr. Salary in the United States

How much does a Clinical Study Project Management Manager, Sr. make in the United States?

As of July 01, 2026, the average salary for a Clinical Study Project Management Manager, Sr. in the United States is $147,000 per year, which breaks down to an hourly rate of $71.

However, a Clinical Study Project Management Manager, Sr.'s salary can vary significantly. Here’s a look at the typical salary range:

  • Top Earners (90th percentile): $175,466
  • Majority Range (25th-75th percentile): $135,300 to $161,900
  • Entry-Level (10th percentile): $124,648
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View as table View as graph 25% $135,300 10% $124,648 90% $175,466 75% $161,900 $147,000 50%(Median) Didn’t find job title? Click

Clinical Study Project Management Manager, Sr. Salaries by Percentile

Annual
Salary
Monthly
Pay
Weekly
Pay
Hourly
Wage
75th Percentile $161,900 $13,492 $3,113 $78
Average $147,000 $12,250 $2,827 $71
25th Percentile $135,300 $11,275 $2,602 $65
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Key Factors That Influence Clinical Study Project Management Manager, Sr. Salaries

A Clinical Study Project Management Manager, Sr.'s salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location, and company size can directly affect your earning potential.

How Experience Level Affects Clinical Study Project Management Manager, Sr. Salaries?

Experience is a primary driver of a Clinical Study Project Management Manager, Sr.'s salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here's how the average salary grows at different career stages:

  • Clinical Study Project Management Supervisor (10+ years): $97,243
  • Clinical Study Project Management Manager (10+ years): $121,645
  • Clinical Study Project Management Manager, Sr. (10+ years): $146,924
  • Clinical Study Project Management Director (10+ years): $167,938
  • VP of Clinical Study Project Management (10+ years): $218,124
Job Role Years of Experience Average Salary
Clinical Study Project Management Supervisor10+ years$97,243
Clinical Study Project Management Manager10+ years$121,645
Clinical Study Project Management Manager, Sr.10+ years$146,924
Clinical Study Project Management Director10+ years$167,938
VP of Clinical Study Project Management10+ years$218,124
$97,243 Clinical ...
$121,645 Clinical ...
$146,924 Clinical ...
$167,938 Clinical ...
$218,124 VP of Cli...
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How Do Clinical Study Project Management Manager, Sr. Salaries Vary from State to State?

Your salary can change significantly depending on where you work. States with a higher cost of living and strong industrial sectors often pay more to attract Clinical Study Project Management Manager, Sr.s. For example, consider the average annual salaries in these key locations:

  • District of Columbia: $162,700.
  • California: $162,100.
  • Massachusetts: $159,900.

Top Paying Cities for Clinical Study Project Management Manager, Sr.s

Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:

  • San Jose: $185,400
  • San Francisco: $183,300
  • Oakland: $179,500

Clinical Study Project Management Manager, Sr. Salary by Company Size: Startups vs. Enterprise

Clinical Study Project Management Manager, Sr. salary potential scales significantly with company size. Data shows that Enterprise companies (5,000+ employees) pay the highest average salary at around $166,710. While startup companies pay approximate $141,429.

Clinical Study Project Management Manager, Sr. Salary by Company Size

Company Size Employees Average Salary
Startup1~50$141,429
Growth Stage51~500$149,460
Established501~5000$161,104
Enterprise5000+$166,710

Clinical Study Project Management Manager, Sr. Salary by Industry: Top Paying Sectors

For Clinical Study Project Management Manager, Sr. roles, the industry you choose can affect earning potential by as much as 60% (the gap between the highest and lowest paying industries). Data shows that the Healthcare and Chemicals sectors offer the strongest compensation, at 40% above the average. In contrast, Clinical Study Project Management Manager, Sr. positions in Pharmaceuticals or Biotechnology typically offer lower base pay, as these industries often view Clinical Study Project Management Manager, Sr. as a support function rather than a direct revenue driver.

The top paying industries for a Clinical Study Project Management Manager, Sr.

Industry Sector Average Annual Salary Average Hourly Rate Pay vs.Avg
Healthcare$205,800$99.040%
Chemicals$161,700$78.010%

Clinical Study Project Management Manager, Sr. Salary: Hourly Rate, Weekly Pay, and Monthly Pay

Understanding how a Clinical Study Project Management Manager, Sr.'s annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.

Last Updated on July 01, 2026

Clinical Study Project Management Manager, Sr. Salary Growth & Career Path

For a Clinical Study Project Management Manager, Sr., the most direct path to higher earnings is advancing to the Clinical Study Project Management Director role. This promotion typically comes with a significant pay increase, bringing the average annual salary to $168,000 - a projected growth of 14% over your current level.

Most common benefits for Clinical Study Project Management Manager, Sr.

Social Security
401(k)
Disability
Healthcare
Pension
Time Off (days)
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FAQ about Clinical Study Project Management Manager, Sr.

1. What industry pays the highest salary for Clinical Study Project Management Manager, Sr.?

The Healthcare industry offers the highest average compensation for Clinical Study Project Management Manager, Sr. roles, with salaries approximately 40% above the market median.

2. How much does a senior Project Manager make at Worldwide Clinical Trials?

The salary for a Senior Clinical Study Project Management Manager ranges from $174,300 to $208,600, with a midpoint of $188,400. This reflects the competitive compensation for this role, which is higher than the previously mentioned average of $132K per year at Worldwide Clinical Trials.

3. How much does a senior clinical Project Manager make in the US?

A Senior Clinical Project Manager in the US typically earns between $174,300 and $208,600, with a median salary around $188,400. While some sources report salaries up to $219,900, the majority of salaries fall within this range, reflecting the competitive nature of the field.

4. How much do PMP project managers make in the US?

PMP Project Managers in the US can expect salaries that vary significantly. For a Clinical Study Project Management Manager, the salary ranges from a minimum of $174,300 to a maximum of $208,600, with a midpoint of $188,400. This reflects the specialized nature of the role compared to general project management positions.

5. What is the highest-paying job in clinical research?

The highest-paying job in clinical research is often the Clinical Study Project Management Manager, Sr., with salaries ranging from $174,300 to $208,600, and a midpoint of $188,400. While biostatistics, regulatory affairs, and pharmacovigilance are lucrative fields, the best fit for you will depend on your unique skills and interests.

6. How much do clinical project managers make in the US?

Clinical Study Project Management Managers in the US earn between $174,300 and $208,600, with a median salary of $188,400. This range reflects the competitive nature of the field, with salaries at the lower end being significantly higher than many other roles.

7. How much do PMP project managers make in the US?

PMP Project Managers in the US earn a competitive salary, with a range for Clinical Study Project Management Managers, Sr. starting at $174,300, a mid-point of $188,400, and a maximum of $208,600. This reflects the specialized nature of the role and the demand for experienced professionals in the field.

Where Does Our Salary Data Come From?

Salary.com provides salary estimates, histograms, trends, and comparisons using data from employer job postings and third-party sources.

We offer detailed salary information across multiple percentiles for your reference. (Click here to learn Why the Salary Midpoint Formula Is Crucial for Achieving Pay Equity.)

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