As of September 01, 2026, the average salary for a Clinical Study Project Management Manager, Sr. in the United States is $147,000 per year, which breaks down to an hourly rate of $71.
However, a Clinical Study Project Management Manager, Sr.'s salary can vary significantly. Here’s a look at the typical salary range:
Clinical Study Project Management Manager, Sr. Salaries by Percentile
| Annual Salary |
Monthly Pay |
Weekly Pay |
Hourly Wage |
|
|---|---|---|---|---|
| 75th Percentile | $161,900 | $13,492 | $3,113 | $78 |
| Average | $147,000 | $12,250 | $2,827 | $71 |
| 25th Percentile | $135,300 | $11,275 | $2,602 | $65 |
A Clinical Study Project Management Manager, Sr.'s salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location and company size can directly affect your earning potential.
Experience is a primary driver of a Clinical Study Project Management Manager, Sr.'s salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here's how the average salary grows at different career stages:
| Job Role | Years of Experience | Average Salary |
|---|---|---|
| Clinical Study Project Management Supervisor | 10+ years | $97,243 |
| Clinical Study Project Management Manager | 10+ years | $121,640 |
| Clinical Study Project Management Manager, Sr. | 10+ years | $146,922 |
| Clinical Study Project Management Director | 10+ years | $167,924 |
| VP of Clinical Study Project Management | 10+ years | $218,097 |
Clinical Study Project Management Manager, Sr. salary potential scales significantly with company size. Data shows that Enterprise companies (5,000+ employees) pay the highest average salary at around $166,624. While startup companies pay approximate $141,351.
| Company Size | Employees | Average Salary |
|---|---|---|
| Startup | 1~50 | $141,351 |
| Growth Stage | 51~500 | $149,383 |
| Established | 501~5000 | $160,996 |
| Enterprise | 5000+ | $166,624 |
Understanding how a Clinical Study Project Management Manager, Sr.'s annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.
| Annual Salary | Monthly Pay | Weekly Pay | Hourly Wage | |
|---|---|---|---|---|
| 75th Percentile | $161,900 | $13,492 | $3,113 | $78 |
| Average | $147,000 | $12,250 | $2,827 | $71 |
| 25th Percentile | $135,300 | $11,275 | $2,602 | $65 |
Next Role
Advancement
For a Clinical Study Project Management Manager, Sr., the most direct path to higher earnings is advancing to the Clinical Study Project Management Director role. This promotion typically comes with a significant pay increase, bringing the average annual salary to $168,000 - a projected growth of 14% over your current level.
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The Healthcare industry offers the highest average compensation for Clinical Study Project Management Manager, Sr. roles, with salaries approximately 40% above the market median.
The salary for a Senior Clinical Study Project Management Manager ranges from $174,300 to $208,600, with a midpoint of $188,400. This reflects the competitive compensation for this role, which is higher than the previously mentioned average of $132K per year at Worldwide Clinical Trials.
A Senior Clinical Project Manager in the US typically earns between $174,300 and $208,600, with a median salary around $188,400. While some sources report salaries up to $219,900, the majority of salaries fall within this range, reflecting the competitive nature of the field.
PMP Project Managers in the US can expect salaries that vary significantly. For a Clinical Study Project Management Manager, the salary ranges from a minimum of $174,300 to a maximum of $208,600, with a midpoint of $188,400. This reflects the specialized nature of the role compared to general project management positions.
The highest-paying job in clinical research is often the Clinical Study Project Management Manager, Sr., with salaries ranging from $174,300 to $208,600, and a midpoint of $188,400. While biostatistics, regulatory affairs, and pharmacovigilance are lucrative fields, the best fit for you will depend on your unique skills and interests.
Clinical Study Project Management Managers in the US earn between $174,300 and $208,600, with a median salary of $188,400. This range reflects the competitive nature of the field, with salaries at the lower end being significantly higher than many other roles.
PMP Project Managers in the US earn a competitive salary, with a range for Clinical Study Project Management Managers, Sr. starting at $174,300, a mid-point of $188,400, and a maximum of $208,600. This reflects the specialized nature of the role and the demand for experienced professionals in the field.
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