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Manufacturing Quality Systems Senior Manager Salary in the United States

How much does a Manufacturing Quality Systems Senior Manager make in the United States?

As of August 01, 2026, the average salary for a Manufacturing Quality Systems Senior Manager in the United States is $130,450 per year, which breaks down to an hourly rate of $63.

However, a Manufacturing Quality Systems Senior Manager's salary can vary significantly. Here’s a look at the typical salary range:

  • Top Earners (90th percentile): $140,403
  • Majority Range (25th-75th percentile): $124,420 to $135,660
  • Entry-Level (10th percentile): $118,930
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View as table View as graph 25% $124,420 10% $118,930 90% $140,403 75% $135,660 $130,450 50%(Median) Didn’t find job title? Click

Manufacturing Quality Systems Senior Manager Salaries by Percentile

Annual
Salary		 Monthly
Pay		 Weekly
Pay		 Hourly
Wage
75th Percentile $135,660 $11,305 $2,609 $65
Average $130,450 $10,871 $2,509 $63
25th Percentile $124,420 $10,368 $2,393 $60
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Key Factors That Influence Manufacturing Quality Systems Senior Manager Salaries

A Manufacturing Quality Systems Senior Manager's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location, and company size can directly affect your earning potential.

How Experience Level Affects Manufacturing Quality Systems Senior Manager Salaries?

Experience is a primary driver of a Manufacturing Quality Systems Senior Manager's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here's how the average salary grows at different career stages:

  • Manufacturing QMS Supervisor (10+ years): $88,718
  • Manufacturing QMS Manager (10+ years): $119,619
  • Manufacturing Quality Systems Senior Manager (10+ years): $130,450
  • Manufacturing QMS Director (10+ years): $179,694
  • VP of Manufacturing QMS (10+ years): $189,737
Job Role Years of Experience Average Salary
Manufacturing QMS Supervisor10+ years$88,718
Manufacturing QMS Manager10+ years$119,619
Manufacturing Quality Systems Senior Manager10+ years$130,450
Manufacturing QMS Director10+ years$179,694
VP of Manufacturing QMS10+ years$189,737
$88,718 Manufactu...
$119,619 Manufactu...
$130,450 Manufactu...
$179,694 Manufactu...
$189,737 VP of Man...
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What Am I Worth?

Top Paying Cities for Manufacturing Quality Systems Senior Managers

Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:

  • San Jose: $164,540
  • San Francisco: $162,740
  • Oakland: $159,310

Manufacturing Quality Systems Senior Manager Salary by Company Size: Startups vs. Enterprise

Manufacturing Quality Systems Senior Manager salary potential scales significantly with company size. Data shows that Enterprise companies (5,000+ employees) pay the highest average salary at around $146,031. While startup companies pay approximate $123,539.

Manufacturing Quality Systems Senior Manager Salary by Company Size

Company Size Employees Average Salary
Startup1~50$123,539
Growth Stage51~500$130,657
Established501~5000$141,019
Enterprise5000+$146,031

Manufacturing Quality Systems Senior Manager Salary by Industry: Top Paying Sectors

For Manufacturing Quality Systems Senior Manager roles, the industry you choose can affect earning potential by as much as 55% (the gap between the highest and lowest paying industries). Data shows that the Biotechnology and Pharmaceuticals sectors offer the strongest compensation, at 25% above the average. In contrast, Manufacturing Quality Systems Senior Manager positions in Transportation or Hospitality & Leisure typically offer lower base pay, as these industries often view Manufacturing Quality Systems Senior Manager as a support function rather than a direct revenue driver.

The top paying industries for a Manufacturing Quality Systems Senior Manager

Industry Sector Average Annual Salary Average Hourly Rate Pay vs.Avg
Biotechnology$163,062$78.025%
Pharmaceuticals$159,149$77.022%
Healthcare$153,931$74.018%
Aerospace & Defense$146,104$70.012%
Energy & Utilities$143,495$69.010%

Manufacturing Quality Systems Senior Manager Salary: Hourly Rate, Weekly Pay, and Monthly Pay

Understanding how a Manufacturing Quality Systems Senior Manager's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.

  • Hourly
  • Monthly
  • Weekly
  • Yearly
  • Table View
Last Updated on August 01, 2026
$124,420
Average $130,450/year
$135,660
$10,368
Average $10,871/month
$11,305
$2,393
Average $2,509/week
$2,609
$60
Average $63/hour
$65
Annual Salary Monthly Pay Weekly Pay Hourly Wage
75th Percentile $135,660 $11,305 $2,609 $65
Average $130,450 $10,871 $2,509 $63
25th Percentile $124,420 $10,368 $2,393 $60

Manufacturing Quality Systems Senior Manager Salary Growth & Career Path

Manufacturing Quality Systems Senior Manager
Clinical GMP Director
Manufacturing QMS Director
VP of Clinical GMP
VP of Manufacturing QMS

Promotions are the fastest way to increase your earnings. As a Manufacturing Quality Systems Senior Manager, you have the following paths for advancement. The table below compares the salary raises for common next-step roles. By comparing these figures, you can choose the career path that best meets your financial goals.

Manufacturing Quality Systems Senior Manager Salary Growth and Career Path
Next Step Role Estimate Salary Projected Raise
Clinical GMP Director $167,800 29%
Manufacturing QMS Director $179,713 38%

Salaries of jobs related to Manufacturing Quality Systems Senior Manager

Most common benefits for Manufacturing Quality Systems Senior Manager

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401(k)
Disability
Healthcare
Pension
Time Off (days)
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Common company salaries for Manufacturing Quality Systems Senior Manager

Here are companies hiring for Manufacturing Quality Systems Senior Manager and their salaries, click below for more details.

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Ready to take the next step in your career? Browse thousands of current Manufacturing Quality Systems Senior Manager job openings on our job board. Use the search bar below to find your perfect match.

United States

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    Columbus, OH

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    Columbus, OH

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FAQ about Manufacturing Quality Systems Senior Manager

1. What industry pays the highest salary for Manufacturing Quality Systems Senior Manager?

The Biotechnology industry offers the highest average compensation for Manufacturing Quality Systems Senior Manager roles, with salaries approximately 25% above the market median.

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