As of August 01, 2026, the average hourly rate for a Medical Affairs Manager in the United States is $65, which translates to an annual salary of about $134,297.
However, the hourly wage can vary significantly based on several factors. Here’s a detailed look at the typical pay range per hour:
Medical Affairs Manager Salaries by Percentile
| Annual Salary |
Monthly Pay |
Weekly Pay |
Hourly Wage |
|
|---|---|---|---|---|
| 75th Percentile | $147,118 | $12,260 | $2,829 | $71 |
| Average | $134,297 | $11,191 | $2,583 | $65 |
| 25th Percentile | $124,246 | $10,354 | $2,389 | $60 |
A Medical Affairs Manager's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location and company size can directly affect your earning potential.
Experience is a primary driver of a Medical Affairs Manager's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here's how the average salary grows at different career stages:
| Levels | Salary |
|---|---|
| Entry Level Medical Affairs Manager | $130,547 |
| Intermediate Level Medical Affairs Manager | $130,997 |
| Senior Level Medical Affairs Manager | $132,497 |
| Specialist Level Medical Affairs Manager | $134,297 |
| Expert Level Medical Affairs Manager | $137,550 |
Medical Affairs Manager salary potential scales significantly with company size. Data shows that Enterprise companies (5,000+ employees) pay the highest average salary at around $150,716. While startup companies pay approximate $127,818.
| Company Size | Employees | Average Salary |
|---|---|---|
| Startup | 1~50 | $127,818 |
| Growth Stage | 51~500 | $135,101 |
| Established | 501~5000 | $145,611 |
| Enterprise | 5000+ | $150,716 |
Understanding how a Medical Affairs Manager's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.
| Annual Salary | Monthly Pay | Weekly Pay | Hourly Wage | |
|---|---|---|---|---|
| 75th Percentile | $147,118 | $12,260 | $2,829 | $71 |
| Average | $134,297 | $11,191 | $2,583 | $65 |
| 25th Percentile | $124,246 | $10,354 | $2,389 | $60 |
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Manages clinical trials and associated research activities for medical product development. Leads study design and execution and the collection and reporting of study data. Advises on and ensures adherence to clinical protocols. Recruits and negotiates fees with clinical investigators. Coordinates regulatory report submissions, monitors compliance, and concludes studies. May require an advanced degree. Typically reports to a director. Manages subordinate staff in the day-to-day performance of their jobs. True first level manager. Ensures that project/department milestones/goals are met and adhering to approved budgets. Has full authority for personnel actions. Typically requires 5 years experience in the related area as an individual contributor. 1-3 years supervisory experience may be required. Extensive knowledge of the function and department processes.
Salary.com salary estimates, histograms, trends, and comparisons are derived from both employer job postings and third-party data sources. We also provide multiple percentiles of salary information for your reference, click here to know Why the Salary Midpoint Formula Is Crucial to Getting Pay Equity Right. With more online, real-time compensation data than any other website, Salary.com helps you determine your exact pay target.
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