As of May 01, 2026, the average salary for a Medical Affairs Manager in the United States is $134,330 per year, which breaks down to an hourly rate of $65.
However, a Medical Affairs Manager's salary can vary significantly. Here’s a look at the typical salary range:
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Medical Affairs Manager Salaries by Percentile
| Annual Salary |
Monthly Pay |
Weekly Pay |
Hourly Wage |
|
| 75th Percentile | $144,522 | $12,044 | $2,779 | $69 |
| Average | $134,330 | $11,194 | $2,583 | $65 |
| 25th Percentile | $119,536 | $9,961 | $2,299 | $57 |
OhioHealth - Marion, OH
OhioHealth - Marion, OH
City of Sunbury, Ohio - Delaware County, OH
Confidential - Columbus, OH
A Medical Affairs Manager's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location and company size can directly affect your earning potential.
Experience is a primary driver of a Medical Affairs Manager's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here's how the average salary grows at different career stages:
| Levels | Salary |
|---|---|
| Entry Level Medical Affairs Manager | $128,810 |
| Intermediate Level Medical Affairs Manager | $129,472 |
| Senior Level Medical Affairs Manager | $131,680 |
| Specialist Level Medical Affairs Manager | $134,330 |
| Expert Level Medical Affairs Manager | $136,916 |
What Am I Worth?
Your salary can change significantly depending on where you work. States with a higher cost of living and strong industrial sectors often pay more to attract Medical Affairs Managers. For example, consider the average annual salaries in these key locations:
Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:
Understanding how a Medical Affairs Manager's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.
| Annual Salary | Monthly Pay | Weekly Pay | Hourly Wage | |
|---|---|---|---|---|
| 75th Percentile | $144,522 | $12,044 | $2,779 | $69 |
| Average | $134,330 | $11,194 | $2,583 | $65 |
| 25th Percentile | $119,536 | $9,961 | $2,299 | $57 |
For a Medical Affairs Manager, the most direct path to higher earnings is advancing to the Medical Affairs Senior Manager role. This promotion typically comes with a significant pay increase, bringing the average annual salary to $169,624 - a projected growth of 26% over your current level.
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Compensation PlanningHere are companies hiring for Medical Affairs Manager and their salaries, click below for more details.
Biotechnology
Biotechnology
Biotechnology
Biotechnology
Biotechnology
Biotechnology
Biotechnology
Biotechnology
Biotechnology
Biotechnology
Biotechnology
Biotechnology
Biotechnology
Biotechnology
Biotechnology
Biotechnology
Biotechnology
Biotechnology
Biotechnology
Biotechnology
Biotechnology
Biotechnology
Biotechnology
Biotechnology
Biotechnology
Ready to take the next step in your career? Browse thousands of current Medical Affairs Manager job openings on our job board. Use the search bar below to find your perfect match.
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A Medical Affairs Manager's earning potential can vary widely depending on several factors, including location, industry, experience, education, and the specific employer. According to the latest salary data by Salary.com, a Medical Affairs Manager earns the most in San Jose, CA, where the annual salary of a Medical Affairs Manager is $169,430.
The highest pay for Medical Affairs Manager is $153,801.
The lowest pay for Medical Affairs Manager is $106,067.
Manages clinical trials and associated research activities for medical product development. Leads study design and execution and the collection and reporting of study data. Advises on and ensures adherence to clinical protocols. Recruits and negotiates fees with clinical investigators. Coordinates regulatory report submissions, monitors compliance, and concludes studies. May require an advanced degree. Typically reports to a director. Manages subordinate staff in the day-to-day performance of their jobs. True first level manager. Ensures that project/department milestones/goals are met and adhering to approved budgets. Has full authority for personnel actions. Typically requires 5 years experience in the related area as an individual contributor. 1-3 years supervisory experience may be required. Extensive knowledge of the function and department processes.
Salary.com provides salary estimates, histograms, trends, and comparisons using data from employer job postings and third-party sources.
We offer detailed salary information across multiple percentiles for your reference. (Click here to learn Why the Salary Midpoint Formula Is Crucial for Achieving Pay Equity.)
With the most extensive online, real-time compensation data available, Salary.com helps you pinpoint your exact pay target.
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