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As of August 01, 2026, the average salary for an Aprn in Missouri is $110,697 per year, which breaks down to an hourly rate of $53.
However, an Aprn's salary can vary significantly. Here’s a look at the typical salary range:
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Aprn Salaries by Percentile
| Annual Salary |
Monthly Pay |
Weekly Pay |
Hourly Wage |
|
| 75th Percentile | $117,222 | $9,769 | $2,254 | $56 |
| Average | $110,697 | $9,225 | $2,129 | $53 |
| 25th Percentile | $104,213 | $8,684 | $2,004 | $50 |
American Oncology Network - Springfield, MO
i4 Search Group - Jefferson City, MO
Boone Health - Macon, MO
i4 Search Group Healthcare - Springfield, MO
An Aprn's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location and company size can directly affect your earning potential.
Experience is a primary driver of an Aprn's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here’s how the average salary grows at different career stages:
| Levels | Salary |
|---|---|
| Entry Level Aprn | $109,617 |
| Intermediate Level Aprn | $110,067 |
| Senior Level Aprn | $112,260 |
| Specialist Level Aprn | $115,216 |
| Expert Level Aprn | $115,744 |
What Am I Worth?
Your salary can change significantly depending on where you work. States with a higher cost of living and strong industrial sectors often pay more to attract Aprns. For example, consider the average annual salaries in these key locations:
Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:
For Aprn roles, the industry you choose can impact your earning potential by as much as 40% (the gap between the highest and lowest paying industries). Data shows that the highest-paying industry, Edu., Gov't. & Nonprofit, offers compensation 20% above the average. Conversely, Aprn positions in Healthcare typically offer lower base pay, as this sector often view Aprn as a support function rather than a direct revenue driver.
| Industry Sector | Average Annual Salary | Average Hourly Rate | Pay vs.Avg |
|---|---|---|---|
| Edu., Gov't. & Nonprofit | $132,837 | $64.0 | 20% |
Understanding how an Aprn's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.
| Annual Salary | Monthly Pay | Weekly Pay | Hourly Wage | |
|---|---|---|---|---|
| 75th Percentile | $117,222 | $9,769 | $2,254 | $56 |
| Average | $110,697 | $9,225 | $2,129 | $53 |
| 25th Percentile | $104,213 | $8,684 | $2,004 | $50 |
Ready to take the next step in your career? Browse thousands of current Aprn job openings on our job board. Use the search bar below to find your perfect match.
VitalCore Health Strategies
Saint Charles, MO
VitalCore Health Strategies | Saint Charles, MO
Job Description. Job Description. Join the VitalCore Team in Missouri. We're people fueled by passion, not by profit. VitalCore Health Strategies (VCHS), a... more
6 Days Ago
Kansas City Hospice & Palliative Care
Kansas City, MO
Kansas City Hospice & Palliative Care | Kansas City, MO
Job Title. Nurse Practitioner. Location. 2800 Clay Edwards Dr, North Kansas City, MO, 64116, United States. Job Category. Healthcare. Industry. Hospice, He... more
6 Days Ago
Cherokee Federal
Saint Louis, MO
Cherokee Federal | Saint Louis, MO
Job Title. Nurse Practitioner. Job Description. A government contract requires that this position be restricted to U.S. citizens. This position requires a ... more
8 Days Ago
Boone Health
Columbia, MO
Boone Health | Columbia, MO
Help Shape the Future of Cardiovascular Care. Boone Health is seeking a dedicated and clinically driven Advanced Practice Registered Nurse to join our expa... more
5 Days Ago
University Health
Kansas City, MO
University Health | Kansas City, MO
Women's Health Nurse Practioner (APRN) - Maternal Fetal Medicine Clinic. University Health 2 (UH2) Kansas City, Missouri. UH1 OB GYN Clinic UHTMC. Full tim... more
8 Days Ago
University Health
Kansas City, MO
University Health | Kansas City, MO
Part-Time Advanced Practice Registered Nurse (APRN) or Physician Assistant (PA) - Primary Care Clinic (Adult & Pediatric). This role is open to experienced... more
7 Days Ago
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