Senior Clinical Data Manager Salary in the United States

How much does a Senior Clinical Data Manager make in the United States?

As of July 01, 2026, the average salary for a Senior Clinical Data Manager in the United States is $138,922 per year, which breaks down to an hourly rate of $67.

However, a Senior Clinical Data Manager's salary can vary significantly. Here’s a look at the typical salary range:

  • Top Earners (90th percentile): $169,671
  • Majority Range (25th-75th percentile): $126,663 to $155,017
  • Entry-Level (10th percentile): $115,502
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View as table View as graph 25% $126,663 10% $115,502 90% $169,671 75% $155,017 $138,922 50%(Median) Didn’t find job title? Click

Senior Clinical Data Manager Salaries by Percentile

Annual
Salary
Monthly
Pay
Weekly
Pay
Hourly
Wage
75th Percentile $155,017 $12,918 $2,981 $75
Average $138,922 $11,577 $2,672 $67
25th Percentile $126,663 $10,555 $2,436 $61
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Key Factors That Influence Senior Clinical Data Manager Salaries

A Senior Clinical Data Manager's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location, education and company size can directly affect your earning potential.

How Experience Level Affects Senior Clinical Data Manager Salaries?

Experience is a primary driver of a Senior Clinical Data Manager's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here's how the average salary grows at different career stages:

  • Entry-Level (less than 1 year): $137,219
  • Early Career (1-2 years): $137,730
  • Mid-Level (2-4 years): $141,476
  • Senior-Level (5-8 years): $147,556
  • Expert (over 8 years): $148,385
Levels Salary
Entry Level Senior Clinical Data Manager$137,219
Intermediate Level Senior Clinical Data Manager$137,730
Senior Level Senior Clinical Data Manager$141,476
Specialist Level Senior Clinical Data Manager$147,556
Expert Level Senior Clinical Data Manager$148,385
$137,219 0 yr
$137,730 < 2 yrs
$141,476 2-4 yrs
$147,556 5-8 yrs
$148,385 > 8 yrs
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What Am I Worth?

Top Paying Cities for Senior Clinical Data Managers

Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:

  • San Jose: $175,222
  • San Francisco: $173,304
  • Oakland: $169,652

What Skills Can Increase a Senior Clinical Data Manager's Salary?

Demanded Skills for the Role:

  • Project Management (Mentioned in 2.56% Job Postings): Project management is the application of processes, methods, skills, knowledge and experience to achieve specific project objectives according to the project acceptance criteria within agreed parameters. Project management has final deliverables that are constrained to a finite timescale and budget.
  • Database Design (Mentioned in 2.07% Job Postings): Overlap to row 560
  • Data Collection (Mentioned in 1.59% Job Postings): Data collection is the process of gathering and measuring information on targeted variables in an established system, which then enables one to answer relevant questions and evaluate outcomes. Data collection is a component of research in all fields of study including physical and social sciences, humanities, and business. While methods vary by discipline, the emphasis on ensuring accurate and honest collection remains the same. The goal for all data collection is to capture quality evidence that allows analysis to lead to the formulation of convincing and credible answers to the questions that have been posed.
See More Skills
Skills Demand Percentage
Project Management 2.56%
Database Design 2.07%
Data Collection 1.59%
What skills can make your compensation higher?
Mastering certain specialized skills can lead to a significant increase in pay. Here are examples of skills and the potential impact they can have on a Senior Clinical Data Manager's salary.
  • Biostatistics: Can increase your salary by up to 5%.
  • Drug Development: Can increase your salary by up to 5%.
  • Programming: Can increase your salary by up to 4%.
Skill Salary Salary % Increase
Biostatistics
$145,868
5%
Drug Development
$145,868
5%
Programming
$144,479
4%
Planning
$144,479
4%
SAS
$144,479
4%
Innovation
$144,479
4%
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Senior Clinical Data Manager Salary by Industry: Top Paying Sectors

For Senior Clinical Data Manager roles, the industry you choose can affect earning potential by as much as 40% (the gap between the highest and lowest paying industries). Data shows that the Biotechnology and Edu., Gov't. & Nonprofit sectors offer the strongest compensation, at 20% above the average. In contrast, Senior Clinical Data Manager positions in Business Services or Healthcare typically offer lower base pay, as these industries often view Senior Clinical Data Manager as a support function rather than a direct revenue driver.

The top paying industries for a Senior Clinical Data Manager

Industry Sector Average Annual Salary Average Hourly Rate Pay vs.Avg
Biotechnology$166,706$80.020%
Edu., Gov't. & Nonprofit$152,814$73.010%

How Education impacts a Senior Clinical Data Manager's Salary?

Your level of education can impact your salary potential. While many Senior Clinical Data Managers enter the field with a Master's Degree or MBA degree, higher education can lead to more specialized and higher-paying roles.

According to our 100% employer-reported salary data, the median salary for a Senior Clinical Data Manager with a Master's Degree or MBA is between $119,184 and $125,657).

Senior Clinical Data Manager Salaries by Degree Level

Typical Education for Senior Clinical Data Manager
Degree Level % of user with this level of education
No Diploma 7.3%
High School 7.3%
Associates 2.9%
Bachelors 49.6%
Masters 32.8%
Doctorate 7.3%
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Senior Clinical Data Manager Salary: Hourly Rate, Weekly Pay, and Monthly Pay

Understanding how a Senior Clinical Data Manager's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.

Last Updated on July 01, 2026

Salary Trends for Senior Clinical Data Manager

Salaries for a Senior Clinical Data Manager can change over time, reflecting shifts in market demand and the overall economy. The median salary decreased from $141,570 in 2023 to around $133,406 in 2025, reflecting changes in demand, location, experience, and the wider economy. For a detailed analysis of Senior Clinical Data Manager salary trends, .

Average Annual Salary of Senior Clinical Data Manager Over Time

2022
$???
2023
$141,570
2024
$136,041
2025
$133,406
2026
$???
2027
$???
Year Average Annual Salary
2022
View More
2023 $141,570
2024 $136,041
2025 $133,406
2026
View More
2027
View More

Most common benefits for Senior Clinical Data Manager

Social Security
401(k)
Disability
Healthcare
Pension
Time Off (days)
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Common company salaries for Senior Clinical Data Manager

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Where Does Our Salary Data Come From?

Salary.com provides salary estimates, histograms, trends, and comparisons using data from employer job postings and third-party sources.

We offer detailed salary information across multiple percentiles for your reference. (Click here to learn Why the Salary Midpoint Formula Is Crucial for Achieving Pay Equity.)

With the most extensive online, real-time compensation data available, Salary.com helps you pinpoint your exact pay target.

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