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Senior Clinical Programmer Salary in the United States

How much does a Senior Clinical Programmer make in the United States?

As of May 01, 2026, the average salary for a Senior Clinical Programmer in the United States is $107,703 per year, which breaks down to an hourly rate of $52.

However, a Senior Clinical Programmer's salary can vary significantly. Here’s a look at the typical salary range:

  • Top Earners (90th percentile): $122,050
  • Majority Range (25th-75th percentile): $97,393 to $115,213
  • Entry-Level (10th percentile): $88,006
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View as table View as graph 25% $97,393 10% $88,006 90% $122,050 75% $115,213 $107,703 50%(Median) Didn’t find job title? Click

Senior Clinical Programmer Salaries by Percentile

Annual
Salary
Monthly
Pay
Weekly
Pay
Hourly
Wage
75th Percentile $115,213 $9,601 $2,216 $55
Average $107,703 $8,975 $2,071 $52
25th Percentile $97,393 $8,116 $1,873 $47
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Key Factors That Influence Senior Clinical Programmer Salaries

A Senior Clinical Programmer's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location, education and company size can directly affect your earning potential.

How Experience Level Affects Senior Clinical Programmer Salaries?

Experience is a primary driver of a Senior Clinical Programmer's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here's how the average salary grows at different career stages:

  • Bioinformatics Programmer/Analyst I (0-2 years): $72,171
  • Bioinformatics Programmer/Analyst II (2-4 years): $97,944
  • Senior Clinical Programmer (4-7 years): $107,685
  • Bioinformatics Programmer/Analyst IV (7+ years): $134,748
Job Role Years of Experience Average Salary
Bioinformatics Programmer/Analyst I0-2 years$72,171
Bioinformatics Programmer/Analyst II2-4 years$97,944
Senior Clinical Programmer4-7 years$107,685
Bioinformatics Programmer/Analyst IV7+ years$134,748
$72,171 Bioinform...
$97,944 Bioinform...
$107,685 Senior Cl...
$134,748 Bioinform...
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What Am I Worth?

Top Paying Cities for Senior Clinical Programmers

Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:

  • San Jose: $135,843
  • San Francisco: $134,353
  • Oakland: $131,523

What Skills Can Increase a Senior Clinical Programmer's Salary?

Demanded Skills for the Role:

  • Analysis (Mentioned in 20.51% Job Postings): Analysis is the process of considering something carefully or using statistical methods in order to understand it or explain it.
  • Python (Mentioned in 3.35% Job Postings): Applying the concepts and algorithms of Python to design, develop and maintain software applications to comply with business requirements.
  • Molecular Biology (Mentioned in 1.31% Job Postings): Molecular biology /məˈlɛkjʊlər/ is a branch of biology that concerns the molecular basis of biological activity between biomolecules in the various systems of a cell, including the interactions between DNA, RNA, proteins and their biosynthesis, as well as the regulation of these interactions. Writing in Nature in 1961, William Astbury described molecular biology as:
See More Skills
Skills Demand Percentage
Analysis 20.51%
Python 3.35%
Molecular Biology 1.31%
What skills can make your compensation higher?
Mastering certain specialized skills can lead to a significant increase in pay. Here are examples of skills and the potential impact they can have on a Senior Clinical Programmer's salary.
  • Molecular Biology: Can increase your salary by up to 7%.
  • Organizing: Can increase your salary by up to 7%.
  • Alignment: Can increase your salary by up to 5%.
Skill Salary Salary % Increase
Molecular Biology
$115,242
7%
Organizing
$115,242
7%
Alignment
$113,088
5%
Innovation
$112,011
4%
Oral Communication
$112,011
4%
Data Management
$112,011
4%
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How Education impacts a Senior Clinical Programmer's Salary?

Your level of education can impact your salary potential. While many Senior Clinical Programmers enter the field with a Associate's Degree degree, higher education can lead to more specialized and higher-paying roles.

According to our 100% employer-reported salary data, the median salary for a Senior Clinical Programmer with a Associate's Degree is between $105,764 and $111,194).

Senior Clinical Programmer Salaries by Degree Level

Typical Education for Senior Clinical Programmer
Degree Level % of user with this level of education
No Diploma 21.6%
High School 78.4%
Associates 0.0%
Bachelors 21.6%
Masters 78.4%
Doctorate 0.0%
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Senior Clinical Programmer Salary: Hourly Rate, Weekly Pay, and Monthly Pay

Understanding how a Senior Clinical Programmer's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.

Last Updated on May 01, 2026

Senior Clinical Programmer Salary Growth & Career Path

For a Senior Clinical Programmer, the most direct path to higher earnings is advancing to the Bioinformatics Programmer/Analyst IV role. This promotion typically comes with a significant pay increase, bringing the average annual salary to $134,800 - a projected growth of 25% over your current level.

Salary Trends for Senior Clinical Programmer

Salaries for a Senior Clinical Programmer can change over time, reflecting shifts in market demand and the overall economy. The median salary decreased from $105,733 in 2023 to around $105,020 in 2025, reflecting changes in demand, location, experience, and the wider economy. For a detailed analysis of Senior Clinical Programmer salary trends, .

Average Annual Salary of Senior Clinical Programmer Over Time

2022
$???
2023
$105,733
2024
$105,506
2025
$105,020
2026
$???
2027
$???
Year Average Annual Salary
2022
View More
2023 $105,733
2024 $105,506
2025 $105,020
2026
View More
2027
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Most common benefits for Senior Clinical Programmer

Social Security
401(k)
Disability
Healthcare
Pension
Time Off (days)
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Common company salaries for Senior Clinical Programmer

Here are companies hiring for Senior Clinical Programmer and their salaries, click below for more details.

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Where Does Our Salary Data Come From?

Salary.com provides salary estimates, histograms, trends, and comparisons using data from employer job postings and third-party sources.

We offer detailed salary information across multiple percentiles for your reference. (Click here to learn Why the Salary Midpoint Formula Is Crucial for Achieving Pay Equity.)

With the most extensive online, real-time compensation data available, Salary.com helps you pinpoint your exact pay target.

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