As of January 01, 2026, the average salary for a Clinical Trial Lead in the United States is $116,967 per year, which breaks down to an hourly rate of $56.
However, a Clinical Trial Lead's salary can vary significantly. Here’s a look at the typical salary range:
Compensation Planning
Develop a Job Description
Pay Equity
2025 Compensation Trend
Smart Recruiting
AI-Powered Talent
A Clinical Trial Lead's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location, education and company size can directly affect your earning potential.
Experience is a primary driver of a Clinical Trial Lead's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here's how the average salary grows at different career stages:
| Levels | Salary |
|---|---|
| Entry Level Clinical Trial Lead | $114,009 |
| Intermediate Level Clinical Trial Lead | $114,239 |
| Senior Level Clinical Trial Lead | $115,160 |
| Specialist Level Clinical Trial Lead | $116,541 |
| Expert Level Clinical Trial Lead | $118,413 |
What Am I Worth?
Your salary can change significantly depending on where you work. States with a higher cost of living and strong industrial sectors often pay more to attract Clinical Trial Leads. For example, consider the average annual salaries in these key locations:
Demanded Skills for the Role:
| Skills | Demand Percentage |
|---|---|
| Initiative | 7.25% |
| Spiritual Care | 4.35% |
| Clinical Practice | 1.45% |
| Skill | Salary | Salary % Increase |
|---|---|---|
|
Clinical Care
|
$167,263 |
43%
|
|
Spiritual Care
|
$154,396 |
32%
|
|
Pediatric
|
$152,057 |
30%
|
|
Commitment
|
$128,664 |
10%
|
|
Facilitation
|
$125,155 |
7%
|
|
Communicates Effectively
|
$120,476 |
3%
|
Your level of education can impact your salary potential. While many Clinical Trial Leads enter the field with a Master's Degree or MBA degree, higher education can lead to more specialized and higher-paying roles.
According to our 100% employer-reported salary data, the median salary for a Clinical Trial Lead with a Master's Degree or MBA is between $108,462 and $115,398).
Clinical Trial Lead Salaries by Degree Level
| Degree Level | % of user with this level of education |
|---|---|
| No Diploma | 50.0% |
| High School | 50.0% |
| Associates | 0.0% |
| Bachelors | 0.0% |
| Masters | 50.0% |
| Doctorate | 50.0% |
Understanding how a Clinical Trial Lead's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.
Last Updated on January 01, 2026Salaries for a Clinical Trial Lead can change over time, reflecting shifts in market demand and the overall economy. The median salary decreased from $99,673 in 2023 to around $96,413 in 2025, reflecting changes in demand, location, experience, and the wider economy. For a detailed analysis of Clinical Trial Lead salary trends, .
| Year | Average Annual Salary |
|---|---|
| 2022 |
View More
|
| 2023 | $99,673 |
| 2024 | $97,649 |
| 2025 | $96,413 |
| 2026 |
View More
|
| 2027 |
View More
|
If your compensation planning software is too rigid to deploy winning incentive strategies, it’s time to find an adaptable solution.
Compensation PlanningHere are companies hiring for Clinical Trial Lead and their salaries, click below for more details.
Ready to take the next step in your career? Browse thousands of current Clinical Trial Lead job openings on our job board. Use the search bar below to find your perfect match.
Get a Salary Increase
Analyze the market and your qualifications to negotiate your salary with confidence.
Search Job Openings
Search thousands of open positions to find your next opportunity.
Adjust Employee Salary
Individualize employee pay based on unique job requirements and personal qualifications.
Price My Industry Jobs
Get the latest market price for benchmark jobs and jobs in your industry.
Salary.com provides salary estimates, histograms, trends, and comparisons using data from employer job postings and third-party sources.
We offer detailed salary information across multiple percentiles for your reference. (Click here to learn Why the Salary Midpoint Formula Is Crucial for Achieving Pay Equity.)
With the most extensive online, real-time compensation data available, Salary.com helps you pinpoint your exact pay target.
Salary.com's CompAnalyst platform offers:
