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Registered Nurses RN Salary in South Carolina

How much does a Registered Nurses RN make in South Carolina?

As of September 01, 2026, the average salary for a Registered Nurses RN in South Carolina is $70,639 per year, which breaks down to an hourly rate of $34.

However, a Registered Nurses RN's salary can vary significantly. Here’s a look at the typical salary range:

  • Top Earners (90th percentile): $86,578
  • Majority Range (25th-75th percentile): $63,422 to $78,982
  • Entry-Level (10th percentile): $56,851
Salary Factors Salary by Experience Related Job Salaries Top Paying Cities Explore Related Jobs

Key Factors That Influence Registered Nurses RN Salaries

A Registered Nurses RN's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how geographic location and company size can directly affect your earning potential.

How Do Registered Nurses RN Salaries Vary from State to State?

Your salary can change significantly depending on where you work. States with a higher cost of living and strong industrial sectors often pay more to attract Registered Nurses RNs. For example, consider the average annual salaries in these key locations:
  • District of Columbia: $83,470.
  • California: $83,153.
  • Massachusetts: $82,045.

Top Paying Cities for Registered Nurses RNs

Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:

  • Spartanburg: $70,383
  • Boiling Springs: $70,386
  • Arcadia: $70,383

Registered Nurses RN Salary by Industry: Top Paying Sectors

For Registered Nurses RN roles, the industry you choose can affect earning potential by as much as 40% (the gap between the highest and lowest paying industries). Data shows that the Energy & Utilities and Biotechnology sectors offer the strongest compensation, at 20% above the average. In contrast, Registered Nurses RN positions in Software & Networking or MFG Nondurable typically offer lower base pay, as these industries often view Registered Nurses RN as a support function rather than a direct revenue driver.

The top paying industries for a Registered Nurses RN

Industry Sector Average Annual Salary Average Hourly Rate Pay vs.Avg
Energy & Utilities$84,767$41.020%
Biotechnology$81,235$39.015%
Insurance$77,703$37.010%
Healthcare$74,171$36.05%

Registered Nurses RN Salary: Hourly Rate, Weekly Pay, and Monthly Pay

Understanding how a Registered Nurses RN's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.

Last Updated on September 01, 2026
$63,422
Average $70,639/year
$78,982
$5,285
Average $5,887/month
$6,582
$1,220
Average $1,358/week
$1,519
$30
Average $34/hour
$38
Annual Salary Monthly Pay Weekly Pay Hourly Wage
75th Percentile $78,982 $6,582 $1,519 $38
Average $70,639 $5,887 $1,358 $34
25th Percentile $63,422 $5,285 $1,220 $30

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Where Does Our Salary Data Come From?

Salary.com salary estimates, histograms, trends, and comparisons are derived from both employer job postings and third-party data sources. We also provide multiple percentiles of salary information for your reference, click here to know Why the Salary Midpoint Formula Is Crucial to Getting Pay Equity Right. With more online, real-time compensation data than any other website, Salary.com helps you determine your exact pay target.

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