As of August 01, 2026, the average annual salary for certified registered nurse in South Carolina is $210,936, equivalent to $101 per hour, $4,056 weekly, or $17,578 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for certified registered nurse in cities like San Jose, Santa Clara, and San Francisco.
Annually Salaries for certified registered nurse in South Carolina vary widely, spanning from $189,698 to $272,899. Most professionals fall between the 25th percentile ($199,819) and 75th percentile ($243,370), while top earners (90th percentile) make $272,899 per year. This $43,551 pay gap underscores opportunities for salary growth through certifications, specialized skills like Planning or Life Support, or targeting high-paying regions like District of Columbia or California.
Location and experience significantly influence earnings. For example, South Carolina certified registered nurse often earn 6.3% lower than national averages due to demand from Fortune 29 companies. However, South Carolina currently ranks 42 nationwide for certified registered nurse job salary. Professionals are advised to focus on high-growth sectors like to offset market challenges.
