As of October 01, 2026, the average annual salary for Chief Scientist in San Diego, CA is $226,452, equivalent to $109 per hour, $4,355 weekly, or $18,871 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for Chief Scientist in cities like San Jose, Santa Clara, and San Francisco.

Annually Salaries for Chief Scientist in San Diego, CA vary widely, spanning from $209,667 to $266,431. Most professionals fall between the 25th percentile ($217,666) and 75th percentile ($247,378), while top earners (90th percentile) make $266,431 per year. This $29,712 pay gap underscores opportunities for salary growth through certifications, specialized skills like Analysis or Bioinformatics, or targeting high-paying regions like District of Columbia or California.

Location and experience significantly influence earnings. For example, San Diego Chief Scientist often earn 2.2% higher than national averages. However, San Diego currently ranks 128 statewide for Chief Scientist job salary. Professionals are advised to focus on high-growth sectors like to offset market challenges.

Based on HR-reported data: a national average with a geographic differential
Chief Scientist Salaries by Percentile
Percentile Salary Location Last Updated
10th Percentile Chief Scientist Salary $209,667 San Diego, CA October 01, 2026
25th Percentile Chief Scientist Salary $217,666 San Diego, CA October 01, 2026
50th Percentile Chief Scientist Salary $226,452 San Diego, CA October 01, 2026
75th Percentile Chief Scientist Salary $247,378 San Diego, CA October 01, 2026
90th Percentile Chief Scientist Salary $266,431 San Diego, CA October 01, 2026
25% $217,666 10% $209,667 90% $266,431 75% $247,378 $226,452 50%(Median) Didn’t find job title? Click
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Chief Scientist

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Job Openings for Chief Scientist in San Diego, CA

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Average Base Salary

Core compensation

 
 
 
217666
247378
226452

Average Total Cash Compensation

Includes base and annual incentives

 
 
 
308745
362932
333823
These charts show the average base salary (core compensation), as well as the average total cash compensation for the job of Chief Scientist in San Diego, CA. The base salary for Chief Scientist ranges from $217,666 to $247,378 with the average base salary of $226,452. The total cash compensation, which includes base, and annual incentives, can vary anywhere from $308,745 to $362,932 with the average total cash compensation of $333,823.

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217666
247378

 

About San Diego, California    According to SDSU professor emeritus Monte Marshall, San Diego Bay is "the surface expression of a north-south-trending, nested graben". The Rose Cany....More

San Diego, California  area prices were up 2.6% from a year ago

Chief Scientist Salary in popular cities: Los Angeles, San Jose, San Francisco

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