As of August 01, 2026, the average annual salary for Clinical Office Assistant in South Carolina is $47,545, equivalent to $23 per hour, $914 weekly, or $3,962 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for Clinical Office Assistant in cities like San Jose, Santa Clara, and San Francisco.

Annually Salaries for Clinical Office Assistant in South Carolina vary widely, spanning from $38,380 to $55,956. Most professionals fall between the 25th percentile ($42,748) and 75th percentile ($51,948), while top earners (90th percentile) make $55,956 per year. This $9,200 pay gap underscores opportunities for salary growth through certifications, specialized skills like Customer Service or Patient Flow, or targeting high-paying regions like District of Columbia or California.

Location and experience significantly influence earnings. For example, South Carolina Clinical Office Assistant often earn 6.3% lower than national averages due to demand from Fortune 50 companies. However, South Carolina currently ranks 42 nationwide for Clinical Office Assistant job salary. Professionals are advised to focus on high-growth sectors like to offset market challenges.

Based on HR-reported data: a national average with a geographic differential
Clinical Office Assistant Salaries by Percentile
Percentile Salary Location Last Updated
10th Percentile Clinical Office Assistant Salary $38,380 SC August 01, 2026
25th Percentile Clinical Office Assistant Salary $42,748 SC August 01, 2026
50th Percentile Clinical Office Assistant Salary $47,545 SC August 01, 2026
75th Percentile Clinical Office Assistant Salary $51,948 SC August 01, 2026
90th Percentile Clinical Office Assistant Salary $55,956 SC August 01, 2026
25% $42,748 10% $38,380 90% $55,956 75% $51,948 $47,545 50%(Median) Didn’t find job title? Click
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Office Assistant

ABS Coastal Insulating Company LLC - Myrtle Beach, SC

Office Assistant

LHH - Greenville, SC

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Clinical Office Assistant

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Location Avg. Salary Date Updated
Location Goose Creek, SC Avg. Salary $48,337 Date Updated August 01, 2026
Location Abbeville, SC Avg. Salary $46,452 Date Updated August 01, 2026
Location Adams Run, SC Avg. Salary $47,716 Date Updated August 01, 2026
Location Aiken, SC Avg. Salary $46,959 Date Updated August 01, 2026
Location Alcolu, SC Avg. Salary $45,148 Date Updated August 01, 2026
Location Allendale, SC Avg. Salary $46,128 Date Updated August 01, 2026
Location Anderson, SC Avg. Salary $46,897 Date Updated August 01, 2026
Location Andrews, SC Avg. Salary $45,983 Date Updated August 01, 2026
Location Arcadia, SC Avg. Salary $47,643 Date Updated August 01, 2026
Location Awendaw, SC Avg. Salary $48,027 Date Updated August 01, 2026
Job Openings for Clinical Office Assistant in South Carolina

Career Path for this job

  1. Down a level:

    Medical Assistant - Non-Certified

    0 - 1 years experience
    High School Diploma or Technical Certificate

  2. This Job:

    Clinical Office Assistant

    1 - 3 years experience
    High School Diploma or Technical Certificate

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