As of August 01, 2026, the average annual salary for injection nurse in South Dakota is $68,827, equivalent to $33 per hour, $1,324 weekly, or $5,736 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for injection nurse in cities like San Jose, Santa Clara, and San Francisco.

Annually Salaries for injection nurse in South Dakota vary widely, spanning from $60,142 to $80,992. Most professionals fall between the 25th percentile ($64,281) and 75th percentile ($75,195), while top earners (90th percentile) make $80,992 per year. This $10,914 pay gap underscores opportunities for salary growth through certifications, specialized skills like Planning or Nursing Process, or targeting high-paying regions like District of Columbia or California.

Location and experience significantly influence earnings. For example, South Dakota injection nurse often earn 9.1% lower than national averages due to demand from Fortune 83 companies. However, South Dakota currently ranks 48 nationwide for injection nurse job salary. Professionals are advised to focus on high-growth sectors like to offset market challenges.

Based on HR-reported data: a national average with a geographic differential
injection nurse Salaries by Percentile
Percentile Salary Location Last Updated
10th Percentile injection nurse Salary $60,142 SD August 01, 2026
25th Percentile injection nurse Salary $64,281 SD August 01, 2026
50th Percentile injection nurse Salary $68,827 SD August 01, 2026
75th Percentile injection nurse Salary $75,195 SD August 01, 2026
90th Percentile injection nurse Salary $80,992 SD August 01, 2026
25% $64,281 10% $60,142 90% $80,992 75% $75,195 $68,827 50%(Median) Didn’t find job title? Click
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Check out injection nurse jobs in South Dakota

Nurse Practitioner

Woundara Wound Care - FORT WAYNE, IN

Nurse Practitioner

Desert Sage Health Centers - MOUNTAIN HOME, ID

REGISTERED NURSE

Siouxland Community Health Center - SIOUX CITY, IA

Registered Nurse

Richmond Healthcare & Rehab Center - RICHMOND, KS

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What is An injection nurse ?

An injection nurse specializes in administering injections and vaccinations, providing essential care in various healthcare settings. Responsibilities include preparing and administering medications, monitoring patients for adverse reactions, and maintaining accurate records of immunizations and treatments. Injection nurses also educate patients about the procedures and potential side effects, ensuring a comfortable experience. Salaries for injection nurses can vary based on factors such as location, experience, and the healthcare facility. On average, injection nurses earn between $60,000 a...

Source: (as of 06/04/2025). Read more from

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Location Avg. Salary Date Updated
Location Deadwood, SD Avg. Salary $75,007 Date Updated August 01, 2026
Location Pierre, SD Avg. Salary $70,002 Date Updated August 01, 2026
Location Watertown, SD Avg. Salary $76,992 Date Updated August 01, 2026
Location Aberdeen, SD Avg. Salary $76,862 Date Updated August 01, 2026
Location Agar, SD Avg. Salary $71,823 Date Updated August 01, 2026
Location Akaska, SD Avg. Salary $76,175 Date Updated August 01, 2026
Location Alcester, SD Avg. Salary $76,297 Date Updated August 01, 2026
Location Alexandria, SD Avg. Salary $76,555 Date Updated August 01, 2026
Location Allen, SD Avg. Salary $76,045 Date Updated August 01, 2026
Location Alpena, SD Avg. Salary $76,685 Date Updated August 01, 2026
Job Openings for injection nurse in South Dakota

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