As of September 01, 2026, the average annual salary for Lead Medical Assistant in South Carolina is $110,247, equivalent to $53 per hour, $2,120 weekly, or $9,187 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for Lead Medical Assistant in cities like San Jose, Santa Clara, and San Francisco.
Annually Salaries for Lead Medical Assistant in South Carolina vary widely, spanning from $86,963 to $132,536. Most professionals fall between the 25th percentile ($98,059) and 75th percentile ($121,914), while top earners (90th percentile) make $132,536 per year. This $23,855 pay gap underscores opportunities for salary growth through certifications, specialized skills like Leadership or Clinical Operations, or targeting high-paying regions like District of Columbia or California.
Location and experience significantly influence earnings. For example, South Carolina Lead Medical Assistant often earn 6.3% lower than national averages due to demand from Fortune 34 companies. However, South Carolina currently ranks 42 nationwide for Lead Medical Assistant job salary. Professionals are advised to focus on high-growth sectors like Edu., Gov't. & Nonprofit to offset market challenges.
