Principal Scientist, Biomarker Development

The Position The Principal Scientist will be responsible for the oversight of one or more Oncology biomarker programs in the early/late development stages of the molecules during life cycle management. The incumbent will lead Biomarker subteams for programs in clinical development, before and after approval, as well as a small laboratory group focusing on predictive biomarker development efforts. As a biomarker subteam leader, the incumbent will represent OBD on global development and life cycle teams and will develop and execute the personalized healthcare (PHC) strategy for the respective therapeutics. The successful candidate is expected to effectively lead cross-functional teams and to publish innovative biomarker or disease focused research in high quality scientific, technical or medical journals as well as present at international meetings. Effectively communicating to and develop collaborative relationships with key investigators and opinion leaders will be an essential part of the assignment to push biomarker sciences forward. Responsibilities: Provide exceptional scientific leadership with in OBD, as well as to other functions, subteams / teams at Genentech / Roche Develop ad effectively manage a small laboratory group, predominantly focused on scientific support for molecule programs Represent the biomarker strategy and plan of an Oncology therapeutic to the late stage project teams (GDT / LCT) and oncology biomarker review forum or decision committee. Lead and drive biomarker related studies and collaborations as well as data analysis and interpretation for an Oncology therapeutic project Drive scientific and technical innovation collaboratively with other members of the Department Participate in, or lead, disease focused translational biomarker programs, or develop a key focus on novel technologies that advance clinical biomarker assessment Publish in high quality scientific, technical or medical journals Represent OBD externally through presentations at key National / International meetings, interactions with our key investigators Manage scientists responsible for disease area biomarker strategies Requirements: PhD, MD or PhD/MD degree in a relevant scientific field (e.g. pathology, molecular biology, cancer genetics, cancer biology, molecular oncology) Experience in clinical drug development and biomarkers is beneficial, including basic or advanced understanding of critical development functions, e.g. Clinical Pharmacology, Regulatory, Safety, Operations, Biostatistics, etc. Experience and understanding of diagnostic product development, particularly in Oncology would highly desirable Consistent record of cutting edge research and / or clinically-related science as evidenced by first- or senior-authored publications in top-tier journals Recognized scientific leadership as documented by references and external presentations Outstanding presentation and communication skills Ability to demonstrate effectiveness and growth in a fast-paced and dynamic environment The expected salary range for this position based on the primary location of California is $141,500 - $262, 900. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below. Benefits #LI-SKILLIAN #ScientistJob Who we are A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work. Unless entitled to a reasonable accommodation under applicable law, employees are required to be fully vaccinated against COVID-19 in accordance with customer requirements, the company’s health and safety obligations and/or applicable law or guidelines. Diversity and Inclusion (D&I) are critical to the success of our company and our impact on society. We believe that by championing diversity of background, thought and experience, we can foster a sense of belonging and provide an environment where every employee feels valued, included, and able to contribute their best for the patients we serve. We’re focused on attracting, retaining, developing and advancing our people to their full potential by rewarding bold ways of thinking and integrating inclusive behaviors into every aspect of our work. Genentech is an equal opportunity employer, and we embrace the increasingly diverse world around us. Genentech prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status and veteran status. For more information about equal employment opportunity, visit our Genentech Careers Homepage. We believe it’s urgent to deliver medical solutions right now – even as we develop innovations for the future. We are passionate about transforming patients’ lives. We are courageous in both decision and action. And we believe that good business means a better world. That is why we come to work each day. We commit ourselves to scientific rigor, unassailable ethics, and access to medical innovations for all. We do this today to build a better tomorrow. We are proud of who we are, what we do, and how we do it. We are many, working as one across functions, across companies, and across the world. We are Roche.