Scientist, In Vitro-Radioconjugate

At AstraZeneca, we turn ideas into life changing medicines. Working here means being entrepreneurial, thinking big, and working together to make the impossible a reality. We’re passionate about the potential of science to address the unmet needs of patients around the world. We commit to those areas where we believe we can really change the course of medicine and bring big new ideas to life. 

We are seeking a highly motivated Scientist with a proven track record of scientific excellence to join our radioconjugate (RC) team in the Tumor Targeted Delivery group within AZ Early Oncology Discovery in Gaithersburg, MD, USA. You will be a key member of a team working to develop novel, targeted radioconjugate therapies and advancing them through early pre-clinical development. You will bring your theoretical and practical expertise to support platform and pipeline RC projects, working with a cross-functional team to deliver pre-clinical datasets to support pipeline progression and platform development. You will have the opportunity to present data and represent the team in project team meetings, platform meetings, and other internal forums. 

Main Duties and Responsibilities 

Working in this laboratory-based position within the Early Oncology Discovery group, you will develop, design, conduct, troubleshoot, and analyze in vitro experiments to validate tool reagents, investigate target biology, and dissect the mechanism of action of these novel cancer therapeutics. You will be expected to support cross-functional teams and work collaboratively with project leaders to ensure the timely generation and dissemination of critical program data. As a highly organized, self-motivated individual with a strong background in laboratory science, you will stay up-to-date with relevant technical and intellectual scientific expertise in tumor biology and cancer modelling and have a genuine passion for this field of research. 

Essential Requirements 

• Bachelor's Degree in a relevant discipline with 5 years of experience OR a Master’s degree with 2 years of experience, recent Master’s graduates may be considered with extensive previous experience and background in a relevant discipline (candidates possessing a Ph.D. degree will not be considered) 

• Extensive knowledge of cell biology, molecular biology, and/or biochemistry in the context of cancer biology, with a strong desire for continued learning 

• Experience with routine cell culture, particularly culture of tumor cells 

• Expertise in molecular- and cell-based methodologies, such as cytotoxicity assays, binding and internalization assays, multicolor flow cytometry, fluorescent and live cell microscopy, ELISA, and Western blotting 

• Works independently with minimal supervision to conduct experiments, analyze data, and prepare results for internal and external presentations and regulatory filings 

• Ability to mentor and teach junior colleagues 

• Excellent communication, presentation, and interpersonal skills and evidence of delivery in a team-oriented, collaborative environment 

• Ensures own work, and work of peers, is compliant with Good Laboratory Practice, Safety, Health, and Environment standards and all other relevant internal AstraZeneca standards and external regulations 

Desirable Requirements 

• Prior experience in the biopharmaceutical industry preferable but not required 

• Experience in molecular cloning and cell line engineering is highly desirable  

• Candidates with experience related to radiation biology, radiochemistry, or radiopharmaceutical therapies would be preferable 

• A proven track record of productivity; contributions to scientific publications in peer-reviewed journals 

About Our Gaithersburg Oncology Hub 

Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world. This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. The modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We are dedicated to creating a culture of inclusion and collaboration. 

The Gaithersburg site offers a variety of amenities to help keep our employees happy and healthy. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center, game rooms, community garden, and more. Here you’ll find newly-designed, activity-based workspaces to suit a variety of working styles while increasing collaboration between teams. 

So, what’s next- 

Are you already envisioning yourself joining our team? Good! We can’t wait to hear from you! 

If you’re curious to know more, please contact Arlene Klingaman, our Talent Acquisition Partner. 

Closing Date:  

Competitive remuneration and benefits apply 

We offer a competitive Total Reward program including a market driven base salary, bonus, and long term incentive. We have a generous paid time off program and a comprehensive benefits package. 

Where can I find out more? 

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