What are the responsibilities and job description for the Research Associate position at Actalent?
Responsibilities:
- Work in collaboration with discovery and preclinical teams to produce raw materials and mRNA products to support in vitro and in vivo preclinical studies.
- Execute analytical testing for non-GMP and GMP release and stability testing for assays such as Appearance, pH, Osmolality, icIEF, CE-SDS, ELISA plate-based methods (Binding, Residual Host Cell Protein, Residual Protein A), and Residual Host Cell DNA (qPCR).
- Support multiscale primary recovery, chromatography and TFF process validation studies to assess process suitability for clinical and commercial manufacturing.
- Review ASQT data and participate in batch release
- Support OOS, deviations, change controls, and CAPA investigations, including the execution of troubleshooting activities, as necessary
- Support evaluation of downstream process robustness through risk assessments, DOE approaches, characterization, and in-process control evaluation in collaboration with MSAT and manufacturing teams.
- Maintain diligent and organized records.
- Clearly communicate results and recommendations to colleagues, team members, and supervisors to support process development decision-making.
Nice to have
Empower, Compass, SoftMax, AccuSEQ, SoloVPE
Biologics
GXP
ELISa
HPLC
qPCR
DNA
Elisa Assay
Analytical Development
Work Environment
This is a 1st shift position. This is a 100% onsite position since they will be working in the lab. This is a very close-knit team and they normally work 7:00am-4:00pm or 7:30am-4:30pm.
Qualifications:
• B.S. or M.S. in chemical engineering, bioengineering, biochemistry, biophysics, biology, or related discipline with 2-4 years of experience, respectively (title can be adjusted based on experience)
• Experience with analytical techniques for protein analysis is highly desired
• Experience with multiple chromatography modalities, column packing and validation, AKTA purifiers and Unicorn software is a plus
• Strong organization, communication, and interpersonal skills are required, with the ability to work both independently and in a collaborative work environment is required
Diversity, Equity & Inclusion
At Actalent, diversity and inclusion are a bridge towards the equity and success of our people. DE&I are embedded into our culture through:
- Hiring diverse talent
- Maintaining an inclusive environment through persistent self-reflection
- Building a culture of care, engagement, and recognition with clear outcomes
- Ensuring growth opportunities for our people
Actalent is an equal opportunity employer.
About Actalent
Actalent connects passion with purpose. We help visionary companies advance their engineering and science initiatives through access to specialized experts that drive scale, innovation, and speed to market. With a network of almost 30,000 engineering and sciences consultants and more than 4,500 clients across the U.S., Canada, Asia, and Europe, Actalent serves many of the Fortune 500. An operating company of Allegis Group, the global leader in talent solutions, Actalent launched as a new specialized engineering and sciences services and workforce solutions brand in 2021.
