Senior Scientist, Drug Product Development

The Altos Institute of Medicine will capture knowledge generated about cell health and programming and develop transformative medicines. We are seeking a highly experienced senior scientist, drug product development, to join the Technical Operations team within the Institute of Medicine. The candidate will work in a highly dynamic and cross-functional environment that will have close collaboration with the Institutes of Science and span multiple therapeutic areas. The successful candidate will lead drug development and manufacturing for Altos' small molecule and oligonucleotide programs.

Responsibilities

• Lead drug product formulation, process development and manufacturing for small molecule and oligonucleotide therapeutics and support drug product development for other modalities
• Establish internal drug product development capabilities to support nonclinical studies
• Manage Contract Manufacturing Organizations to deliver products for nonclinical studies and clinical trials
• Foster strong partnerships with Institutes of Science, development sciences, clinical, regulatory, program management, science integrations, business development, legal and finance
• Ensure material specifications, process capabilities, yields, and manufacturing and scale-up strategies are sound for future Altos drug products
• Perform troubleshooting and data analysis to solve technical problems in manufacturing to ensure manufacturing output and product quality
• Support and lead risk assessments and manufacturing deviation investigations
• Author and review Standard Operating Procedures, specifications, regulatory filing, or other controlled documents as needed.
• Actively contribute to a team culture that promotes continuous improvement, ownership, professional growth, and inclusion

Qualifications

• Ph.D. in chemistry, pharmaceutical sciences, chemical engineering, or related fields. Minimum 6 years of experience in drug product development and manufacturing
• Highly experienced in formulation, process development and manufacturing for small molecules
• Experienced in achieving CMC deliverables through outsourcing to Contract Manufacturing Organizations
• Experience in preformulation characterization and analytical testing is preferred
• Ability to work in a dynamic environment, with a willingness to learn new skills and adapt to shifting priorities and tasks
• A critical thinker with the ability to analyze possibilities and solutions and make pragmatic trade-offs, as well as a big-picture innovator who can identify opportunities and is comfortable with ambiguity
• Strong communication and collaboration skills. Build effective relationships and partnerships with internal and external stakeholders

The salary range for Redwood City, CA:

• Senior Scientist I:$148,000 - $212,400
• Senior Scientist II: $177,000 - $253,200

Exact compensation may vary based on skills, experience, and location.

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