Job Posting for Translational Scientist (ddPCR Assays) at Appia Bio
About the Role
Appia Bio is seeking a highly motivated scientist to join our Translational Medicine Team. The individual will be responsible for development of translational biomarker assays to support clinical trials for our CAR-NKT products.
Responsibilities
Design, develop and optimize clinical biomarker assays with focus on ddPCR and molecular/transcriptome profiling to determine pharmacokinetics, pharmacodynamics, safety and efficacy of CAR-NKT products.
Work with internal teams, CROs and collaborators to validate and implement biomarkers for clinical trials.
Analyze, interpret, and present clinical biomarker data to key stakeholders.
Effectively collaborate with cross-functional teams to advance early-stage projects into clinical development.
Act as a technical expert in translational biomarker assays and provide guidance to internal and external collaborators.
Ensure that all biomarker assays are performed in timely manner with appropriate documentation.
Evaluate new technologies and assays that enhance identification and understanding of predictive biomarkers associated with clinical response.
Qualifications
Ph.D. in immunology, biology, or related discipline with 3 - 5 years of experience within biotech or pharmaceutical industry.
In-depth knowledge of translational medicine and clinical biomarkers in drug development.
Strong hands-on experience and expertise in molecular biology related technologies, especially ddPCR and qPCR.
Experience in next generation sequencing, e.g., bulk and single cell RNAseq, and other genomic platforms is highly preferred.
Experience in techniques commonly used in translational biomarker assays, such as flow cytometry, IHC, ELISA, and multiplex assays (e.g., MSD, Luminex) is a plus.
Demonstrated ability to work efficiently with multitasking capability.
Excellent communication and presentation skills, capable of conveying technical information in a clear and thorough manner.
Salary.com Estimation for Translational Scientist (ddPCR Assays) in Culver City, CA
$81,294 to $103,588
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