Bioinformatic Scientist

Overview

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

Benefits We Offer:

• 100% Medical, Dental & Vision Coverage for Employees
• Paid Time Off and Paid Holidays
• 401K match up to 5%
• Educational Benefits for Career Growth
• Employee Referral Bonus
• Flexible Spending Accounts:
  • Healthcare (FSA)
  • Parking Reimbursement Account (PRK)
  • Dependent Care Assistant Program (DCAP)
  • Transportation Reimbursement Account (TRN)

 

Overview Axle is seeking a highly ambitious, adaptable, structured, and detail oriented  Bioinformatic Scientist to join our vibrant team at the National Institutes of Health (NIH), National Institute of Allergy and Infectious Diseases (NIAID), Division of Intramural Research (DIR), The Center for Human Immunology (CHI), and Integrated Data Sciences Section (IDSS) in Bethesda, MD.  Responsibilities:Provide bioinformatic analysis and data interpretation, programming, and troubleshooting support to the CHI in the dissemination of research data.

• Perform computational data analysis and data management. Specifically, provide bioinformatics support to include but not limited to:
  • Omic data analysis, primarily resulting from NGS data generation (Single cell and spatial transcriptomic sequencing, including scRNA-seq, scCITE-seq, scATAC-seq, immune repertoire, 10X Visium, etc.; whole-exome and whole-genome variant analysis; bulk RNA-seq; ChIP-Seq, etc.)
  • Statistical modeling, scripting and biological data interpretation
  • Integration of research and clinical data for analysis
  • Scripting for data transformation, QC, and preprocessing of high-dimensional research data, integration of research and clinical data management, transformation, and automation of complex data analysis, clinical data curation and medical informatics in support of large scale clinical and omic research initiatives
• Work with wet lab staff on experimental design, workflow development, troubleshooting, data analysis, and drafting of manuscripts.
• Address bioinformatics, scientific computing, and data analysis needs of collaborators with the Center for Human Immunology (CHI) by lending expertise in the proper statistical design of biological experiments involving high-throughput technologies, data mining and knowledge discovery techniques, and data workflow applications development as well as performing omic (genomic/NGS, proteomic, etc.) data analysis for research activities and providing statistical and scientific consultancy for omic experimental design, data collection, and platform considerations.

Experience Required / Requirements:

• Master's degree; at least 3 years of experience directly related to the duties and responsibilities specified. (Ph.D. with postdoctoral experience preferred)
• Knowledge and understanding of the principles, concepts, methods, and standards of statistical research, and the ability to plan, create, program, and manage complex data analyses.
• Knowledge of current and emerging trends in bioinformatics methods applied to genomics and proteome data.
• Experience working in a laboratory or clinical setting is a plus.
• Experience working with single cell data is strongly preferred.
• Experience working with Flow Cytometry data is a plus.
• Proficient in one or more of bioinformatics programming/scripting languages such as R, Python, etc.
• Knowledge of scientific reporting and manuscript preparation requirements and standards.
• Ability to work in a team environment to design, analyze, and report on research projects.
• Strong analytical communication, critical thinking, and problem-solving skills.
• Strong focus and quality and timely delivery of work.
• Expertise with Microsoft office (Word, Excel, etc.)
• Ability to obtain and maintain a Public Trust Security clearance.

Disclaimer:The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact: careers@axleinfo.com