Bioprocess Development Senior Fermentation Engineer

Department

48 - Bioprocess Development

Employment Type

Full Time

Location

Redwood City, CA

Workplace type

Onsite

Description

Codexis, a biotechnology company based in Redwood City, CA, is looking to hire a Senior Fermentation Engineer.

Codexis is a leading enzyme engineering company leveraging its proprietary CodeEvolver® technology platform to discover, develop and enhance novel, high-performance enzymes and other classes of proteins. Codexis enzymes solve for real-world challenges associated with small molecule pharmaceuticals manufacturing and nucleic acid synthesis. The Company is currently developing its proprietary ECO Synthesis™ platform to enable the scaled manufacture of RNAi therapeutics through an enzymatic route. Codexis enzymes can drive improvements, such as higher yields, reduced energy usage and waste generation, improve efficiency in manufacturing and greater sensitivity in genomic and diagnostic applications.

To meet the goals we’ve set for ourselves, we look for individuals who are driven, eager to grow and ready to embrace meaningful challenges. We empower employees to be authentic, ambitious, agile and have the courage to take action where they can make a positive impact.

Come join us on this journey to transform the enzyme engineering landscape for the betterment of human health.

About the Opportunity: The Senior Fermentation Engineer will join our Upstream Bioprocess Development team and will be responsible for the design & execution of fermentation experiments for development of new bioprocesses. The person will play a leading technical role in project management of fermentation programs within the group. In addition, the Sr. Fermentation Engineer will be responsible for tech transferring bioprocesses to CRO/CMOs. They will collaborate cross functionally with members of the Technical Operations team. The position will be on-site in Redwood City. If any of the below describes you, we would love to meet you!

• Passionate about Fermentation and the role it plays in translating scientific discovery into commercial reality.
• Enjoys cross-functional collaboration, teamwork, and mentorship. In addition, has a passion for technical project management.
• Enjoys fermentation process development.
• Strong safety mindset in a fermentation environment and have a strong attention to detail.
  
  
  

In This Role You Will Be Responsible For

• Lead the development of new fermentation bioprocesses utilizing E. coli as an expression host for production of enzymes for Pharmaceutical Manufacturing & Life Science applications.
• Hands-on running bench-scale bioreactors, performing bench experiments, and providing mentorship/management to Research Associates & Engineers in the bioprocess development group.
• Lead the authorship of tech transfer packages and transferring processes to CRO/CMOs.
• Following safety best practices and leading implementation of new safety processes.
• Routinely present technical information to various audiences both internal and external to Bioprocess Development & Codexis.
  
  
  

The Essential Requirements Of The Job Include

• M.S or B.S. in Chemical or Bioprocess Engineering, or related discipline with a minimum of 8-10 years of relevant industry experience respectively.
• Hands-on experience with bench scale fermentation for production of recombinant proteins in microbial hosts. Solid understanding of microbial physiology in the context of fermentation.
• Experience with fermentation control software troubleshooting and programing new control strategies.
• Exposure to pilot and commercial scale fermentation and demonstrated technical ability to understand and solve engineering issues involved during scale up. Previous experience with authoring tech transfer packages and providing oversight to CRO/CMOs.
• Experience with leading multiple fermentation-focused projects simultaneously and demonstrated experience of leading projects from start to finish.
  
  
  

Additional experience that would be valuable for this role includes:

• Experience working under a quality system (e.g. ISO, GMP) or manufacturing experience/exposure.
• Hands-on experience with primary recovery of enzymes and knowledge of downstream purification unit operations.
• Exposure to Cost of goods (COGs) and technoeconomic analysis (TEA) for bioprocesses.
• Development of high throughput solutions to bioprocessing e.g. HT fermentation systems. Expertise with Design of Experiments and handling large data sets.
  
  
  

CODEXIS PAY TRANSPARENCY: The anticipated salary range for candidates who will work in Redwood City is $138,500 to $170,000. The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience within the job, type and length of experience within the industry, education, etc. Codexis is a multi-state employer, and this salary range may not reflect positions that work in other states .

What can Codexis offer you?

• Medical, Dental and Vision Insurance
• Basic Life, AD&D, Short- and Long-Term Disability Insurance
• 401k with Company Match up to 4%
• Company Equity
• Generous Paid Time Off including 18 Company Holidays (with a summer and winter shutdown), Vacation, and Wellness Time
• Annual Lifestyle Account for reimbursement of fitness programs, equipment and more
• Employee Stock Purchase Program (ESPP)
• Flexible Spending Accounts (Commuter/Parking, Dependent Care & Healthcare)
• Student Debt Program (Company Contribution to Loans)
• Mental Health Wellness Program
• Subsidized onsite lunch program
• Onsite Gym Facilities
• Paid Parental Leave
• And More!
  
  
  

About Codexis Inc

Why join Codexis?

At Codexis we offer a very competitive compensation package and beyond excellent benefits! We foster career growth, continued education and upskilling through our mentorship program and learning and development opportunities. You will learn and work alongside inspirational leaders and colleagues who are equally passionate about our mission and committed to fostering an inclusive, growth-centered, and rewarding culture. Diversity is valued and mutual trust is of paramount importance to the ethos at Codexis. The people, the culture and working with others with a common goal is what makes Codexis a great place to work.

For more information, visit www.codexis.com.

NO AGENCIES OR THIRD PARTIES

Codexis is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status.

Salary : $138,500 - $170,000