What are the responsibilities and job description for the Scientist - Histology (IHC) position at Charles River?
For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.
Job Summary
We are seeking a Scientist - Histology (IHC) for our Histology department in our Mattawan, MI location.
A Scientist is responsible for supporting the pathology services departments by performing advanced necropsy or histology procedures, study development procedures, and for providing mentorship and training to Associate Scientists and staff. The Individual in this role may also function as the Contributing Scientist or Principle Investigator, responsible for the development of study specific procedures and applicable protocols/plans in accordance with company standard operating procedures (SOPs), industry regulatory guidelines, and budgetary guidelines as business and scientific needs require.
The pay range for this position is $90,000-95,000/year USD. Please note that salaries vary within the range based on factors including, but not limited to, experience, skills, education, certifications, and location.
Essential Duties and Responsibilities
- Performs advanced histology and/or necropsy preparation procedures on a variety of biological specimens using requisite instrumentation and techniques; performs microscopic review on a variety of specimens.
- Provides scientific insight, researches, and evaluates the technical feasibility of implementing new techniques to supplement existing laboratory capabilities; develops, validates, implements, and/or evaluates methods and techniques for production environment process improvement; documents procedures and materials.
- Contributes to the development, writing, and reviewing of study protocols, attends the pre-initiation meetings for related studies, assists with analyzing study needs, and provides expertise to study directors, sponsor representatives, QA personnel and management; serves as project lead for studies that require advanced techniques.
- Consults with internal and external customers regarding scientific issues.
- Prepares publications and presents scientific information in areas of expertise for clients, internal customers, and at conferences.
- Reviews and/or approves new or revised SOPs, forms, or other procedural documents.
- Performs laboratory investigations, procedural troubleshooting, quality observations, and improvements within good laboratory practices, non-GLP practices, and departmental processes.
- Provides training and mentorship to associate scientists and staff.
- Assists with providing cost estimates for components of applicable studies.
- Validates software and may serve as an application owner (AO) or subject-matter expert for applications used with departmental instruments.
- May oversee histology processing and validation of studies as a principle investigator, study director, or contributing scientist, as assigned.
- Monitors technical conduct and efficiency of staff and guests within the laboratory and contributes to a constructive study experience for sponsors.
- Collects, documents, analyzes, reviews, and verifies data on forms or in electronic data capture systems; recognizes method and data issues and communicates them to management to minimize study impact, collates data into the study book for archiving and study reports.
- Performs quality control procedures, calibrates, maintains, cleans, and troubleshoots laboratory instrumentation and equipment.
- Receives, inspects, processes, stores, and maintains documentation of biological specimens.
- Other duties as assigned such as providing oversight of the work in the supervisor’s absence.
Job Qualifications
- HS/GED in relevant field, with 10 or more years of relevant experience; Histotechnician (HT)/Histotechnologist (HTL) certification required; or, Bachelor’s/Master’s degree with 8 or more years of relevant experience; HT/HTL certification required.
- Two or more years IHC experience required.
- An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.
- Demonstrated ability to perform complex and advanced necropsy or histology techniques.
- Demonstrated ability to explain scientific relevance of a necropsy or histology technique as it relates to the purpose of a study.
- Exemplary level of expertise in troubleshooting necropsy and histology techniques to preserve the integrity of a study.
- Ability to communicate verbally and in writing at all levels inside and outside the organization.
- Basic familiarity with Microsoft Office Suite.
- Computer skills, commensurate with Essential Functions, including the ability to learn a validated system.
- Ability to work extended hours beyond normal work schedule to include, but not limited to evenings, weekends, extended shifts, and/or extra shifts; sometimes on short notice.
- Ability to work under specific time constraints.
About Safety Assessment
Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market. Each year approximately 300 investigational new drug (IND) programs are conducted in our Safety Assessment facilities.
About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.
With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world.
At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of 86% of the drugs approved by the FDA in 2021.
We’re committed to providing benefits that elevate your quality of life. Based on your position these may include: bonus/incentives based on performance, 401K, paid time off, stock purchase program, Health and wellness coverage, employee and family wellbeing support programs, and work life balance flexibility.
Equal Employment Opportunity
Charles River Laboratories is an Equal Opportunity Employer - all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.
If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to crrecruitment_US@crl.com. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications.
For more information, please visit www.criver.com.
Salary : $1,000 - $1,000,000