Associate II, Process Development

About CTMC

CTMC is a pioneering biotech joint venture, formed by National Resilience and MD Anderson Cancer Center, and located in the renowned Texas Medical Center. Our mission is to accelerate cell therapies from bench to bedside. We offer a wide range of cell therapy modalities, including CAR-T, TIL, ETC, and TCR-T. Our expert team collaborates closely with MD Anderson’s research and clinical faculty, bringing impactful cell therapies to cancer patients.

In our first year alone, we have filed four INDs, each ahead of schedule, demonstrating our commitment to delivering innovative treatments to patients with speed and precision. Our alliance with National Resilience, an ambitious biomanufacturing organization that has raised $2 billion in two years, enables us to remain at the forefront of biomanufacturing practices, leveraging advanced technology and processes to deliver exceptional results.

Our state-of-the-art, 60,000 sq. ft. facility in the Texas Medical Center is staffed by an integrated team of over 80 industry veterans and scientists who are passionate about bringing life-saving cures to patients. Our unique joint venture structure, with two highly established partners, provides us with the financial stability and long-term horizon to achieve our mission.

At CTMC, we value our employees and offer a variety of development opportunities within our organization. We foster a team-first culture and a balanced work-life environment to ensure our staff is energized and engaged in our mission. If you share our passion for advancing the frontiers of medical science with innovative therapeutics and want to join a highly dedicated team committed to delivering novel cures to patients, we invite you to submit your application. We look forward to hearing from you and exploring how your skills and expertise can help us achieve our mission.

Role Summary

CTMC is currently in search of an Associate II, Process Development with a strong interest in Cell Therapy to become an integral part of our dynamic Process Development team. In this position, you will play a key role as a team member within our CAR-T and/or TIL groups. The main role focus will be on executing experiments that provide the foundation for protocols aimed towards clinical applications.

This role presents an exciting opportunity to collaborate closely with a highly skilled ensemble of industry professionals and scientists. The successful candidate will work with cutting-edge equipment and advanced techniques to assist with the development and optimization of CAR-T and TIL therapies that aim to revolutionize the treatment of both solid and hematological cancers.

Responsibilities

• Support the execution of cell therapy process development studies for process understanding and optimization.
• Perform planned experimental work, including but not limited to cell culture, viral transduction, and cryopreservation associated with the projects. Develops technical expertise with T-cell manufacturing processes.
• Learn and train on new equipment and protocols, including automated and semi-automated systems.
• Assist with training of manufacturing staff on new protocols being introduced into the GMP space.
• Maintain accurate and up to date records of laboratory activities using electronic laboratory notebooks.
• Assist in drafting and editing of manufacturing batch records and technical reports.
• Assist with shipments of process development samples.
• Provide written or verbal technical support including protocols or slide decks as needed. May be asked to present to internal lab meetings.
• Maintain and order stocks lab supplies and reagents, as well as perform other lab organization duties.
• Collaborate effectively with members of the viral vector and cell therapy process development and analytical development teams.
• Other duties as required.

Qualifications/Skills

• Bachelor’s degree in related scientific / engineering field.
• 1 yr.’s. of relevant experience required, 2 yr.’s preferred or combination of education and relevant experience comprising of process development of cellular therapies or manufacturing which may include viral vectors and / or other biologics modalities.
• Excellent aseptic technique required.
• Experience with accurate laboratory calculations and conversions required.
• Demonstrated ability to collaborate effectively in a multi-disciplinary team.
• Demonstrated strong communication skills, interpersonal skills, and a superior drive for results.
• Excellent written, oral, interpersonal and presentation skills and the ability to effectively interface with scientists and other associates.
• Excellent judgment and creative problem-solving skills, including negotiation and conflict resolution skills.
• Able to carry out planned laboratory activities under supervision.
• Able to work a flexible schedule including some weekend and holiday work as needed.

Working Conditions, Equipment, Physical Demands

Physical Demands-

• Frequent sitting, standing, walking.
• Carrying packages and moving bins and boxes, lifting up to 10 lbs.

The physical demands and work environment that have been described are representative of those an employee encounters while performing the essential functions of this position. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions in accordance with the Americans with Disabilities Act.

The above job description is an overview of the functions and requirements for this position. This document is not intended to be an exhaustive list encompassing every duty and requirement of this position; your supervisor may assign other duties as considered necessary.