Jr. Bioinformatics Scientist

GAP Solutions, Inc.
Bethesda, MD Full Time
POSTED ON 4/19/2022 CLOSED ON 5/14/2022

What are the responsibilities and job description for the Jr. Bioinformatics Scientist position at GAP Solutions, Inc.?

Provide services as a Jr. Bioinformatics Scientist in support of the overall functions of the Vaccine Research Center (VRC), Structural Bioinformatics Core (SBIS) within the National Institute of Allergy and Infectious Diseases (NIAID).


Duties and Responsibilities:

  • Design and develop in silico analysis tools providing biological insight of vaccine targets including (but not limited to) HIV-1, SARS-CoV-2 spike, Influenza, Dengue/Zika, SIV, Lassa virus and other emerging pathogens.
  • Utilize computer simulation expertise such as molecular dynamic and monte carlo simulations to solve protein structures’ dynamics and mechanism of protein-protein interaction.
  • Develop and improve an in silico tool to quantify glycan density of glycoprotein and find out correlations with antibody-antigen properties (e.g., immunogenicity, antigenicity, antibody-antigen recognition distance).
  • Develop web-based servers of in-house developed in silico tools.
  • Apply advanced sampling skills such as steered and targeted molecular dynamics simulation approach to evaluate transition state between state 2 and state 3 of HIV-1.
  • Serve as expert to identify critical/biological findings of experimental data and collaborate with other scientists.
  • Utilize High performance computing (HPC) to bring the state-of-the-art techniques such as machine learning, artificial intelligence, deep learning to vaccine target protein design.
  • Provide scientific expertise to facilitate protein and vaccine design.
  • Publish the findings and analysis in peer-reviewed journals and present at scientific conferences.

Basic Qualifications:

  • This position requires a PhD in Computational Biology/Chemistry or a related field and 1-2 years of postdoctoral experience.

Minimum Qualifications:

  • Ability to communicate effectively, orally and in writing, with non-technical and technical staff
  • Detail-oriented and possess strong organizational skills with the ability to prioritize multiple tasks and projects

  • This job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required by this position.

To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.


GAP Solutions provides reasonable accommodations to qualified individuals with disabilities. If you need an accommodation to apply for a job, email us at recruiting@gapsi.com. You will need to reference the requisition number of the position in which you are interested. Your message will be routed to the appropriate recruiter who will assist you. Please note, this email address is only to be used for those individuals who need an accommodation to apply for a job. Emails for any other reason or those that do not include a requisition number will not be returned.

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