Principal Scientist and Group Leader, Antibody Engineering

The Position

We are seeking an exceptional Principal Scientist to join Genentech's Department of Antibody Engineering. The successful candidate will head their own lab and lead collaborative multi-disciplinary teams to design, validate, and advance next-generation protein therapeutics that address major unmet medical needs into clinical development. This position will focus on biologies that are not readily addressable with conventional IgGs, potentially involving agonizing or inhibiting pathways in a tissue-, cell-, or context-selective fashion, or enabling therapeutic delivery to regions not readily accessible to standard antibodies. The research will sit at the interface between technology and biology, including defining important therapeutic problems, identifying and applying molecular designs to address them, and balancing biological activity with the practical needs of drug development. Our new Scientist will help shape the future of our antibody drug capabilities, and will be expected to present their research externally and publish in peer-reviewed journals.

Who You Are

We are seeking highly motivated and self-driven candidates with a passion for innovation, creativity, and commitment to translational science and drug development. A PhD is required, and postdoctoral training is strongly preferred. We encourage applications from candidates with extensive prior experience as well as those coming directly from exemplary postdoc careers. Ideal applicants will excel in protein engineering methodologies and be well-versed in biology. Research experience with antibodies is not essential. The successful candidate will have demonstrated a sustained record of productivity and substantive scientific contributions as determined by consistent high-impact publications, patent inventorship, and/or external presentations. Candidates need to be team-oriented, collegial, and have strong interpersonal and communication skills.

Relocation benefits are available for this job posting.

The expected salary range for this position based on the primary location of South San Francisco, CA is $141,500 - $262,900. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Genentech is an equal opportunity employer, and we embrace the increasingly diverse world around us. Genentech prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status and veteran status.

Genentech requires all new hires to be fully vaccinated against COVID-19 as of their start date. This requirement is a condition of employment at Genentech, and it applies regardless of whether the position is located at a Genentech campus or is fully remote. If you are unable to receive the vaccine due to a disability or serious medical condition, or because it is prohibited as a result of your sincerely held religious beliefs, you will have an opportunity to request a reasonable accommodation.