Research Technician, Neurobehavior – Hoekstra Lab

Primary Work Address: 25 Francis Avenue, Cambridge, MA, 02138 Current HHMI Employees, click here to apply via your Workday account. We are seeking a Research Technician to support the lab of Dr. Hopi Hoekstra in the Departments of Molecular and Cellular Biology and Organismic and Evolutionary Biology at Harvard University. The lab is a collaborative and interdisciplinary environment studying the evolution of the neurobiology and behavior of deer mice. More information on the lab can be found on their website. The Research Technician will collaborate closely with two post-doctoral fellows to support two research projects within the lab. These projects will focus on identifying the neural basis of behavioral differences between closely-related deer mouse species. The technician will be involved with experiments related to deer mouse behavior, single-cell RNA-sequencing, molecular neurobiology, and brain/spinal cord histology. There may be opportunities for training in computational data analysis and field work, depending on the project’s needs and candidate’s interests. The ideal candidate should be enthusiastic about contributing to a neuroscience project, eager to learn and become proficient in new techniques and approaches, and able to communicate effectively with lab members. The two main projects we are looking for support on are: (1) investigation of the neural basis of a dramatic, innate climbing difference between deer mice that evolved in forests and those that evolved in prairies, and (2) investigation of the neural basis of mating systems in deer mice. Day-to-day the candidate will be responsible for performing experiments related to these two main projects, attending lab meetings, and performing other lab support tasks. The specific duties of the candidate can be modified based on the candidate’s career goals and interests, especially following the first year. We are ideally targeting candidates looking to commit to the lab at least 2-3 years before moving on to your next opportunity. If you’re interested, there is the opportunity for field work – however, that is not a requirement of the role. Previous research technicians from the Hoekstra lab have been co-authors on major scientific publications, depending on their contribution to the research. What You’ll Do: Work efficiently and cooperatively with a team of researchers in experiments involving the following: Deer mouse behavior Single-cell sequencing library preparation Histology to assess gene and protein expression Microscopy to analyze histology data Molecular biology techniques (PCR, qPCR, genotyping) Collaborate with lab members to analyze results, address technical problems, consulting the scientific literature if needed Maintain a precise record of lab work Assist with other support duties relating to lab operations as required Skills You Bring: Bachelor’s degree in the life sciences or related discipline Previous experience with any of the following standard molecular biological techniques or familiarity with underlying scientific principles is a plus but not necessary: Molecular biology techniques (PCR, qPCR, genotyping) Working with rodent behavior models Sequencing library preparation Cryosectioning/histology Comfort with and ability to work with rodent models Strong multitasking skills and time management Strong communication skills Ability to apply experience to new techniques and protocols and learn complex tasks with general instruction Ability to identify areas of confusion and seek help when needed Strong enthusiasm for developing new skills and expertise Exemplary organizational skills and attention to detail Ability to follow instruction with an eagerness to learn, grow professionally, and be mentored Proficiency with Microsoft Office applications Ability to use good judgment in managing deadlines and responding to inquiries Physical Requirements Remaining in a normal seated or standing position for extended periods of time; reaching and grasping by extending hand(s) or arm(s); dexterity to manipulate objects with fingers, for example using a keyboard; communication skills using the spoken word; ability to see and hear within normal parameters; ability to move about workspace. The position requires mobility, including the ability to move materials weighing up to several pounds (such as a laptop computer or tablet). Work may involve possible exposure to malodorous vapors, low dose radiation, contamination by toxic chemicals and acids and presence of carcinogenic substances. Persons with disabilities may be able to perform the essential duties of this position with reasonable accommodation. Requests for reasonable accommodation will be evaluated on an individual basis. Please Note: This job description sets forth the job’s principal duties, responsibilities, and requirements; it should not be construed as an exhaustive statement, however. Unless they begin with the word “may,” the Essential Duties and Responsibilities described above are “essential functions” of the job, as defined by the Americans with Disabilities Act. Compensation and Benefits Our employees are compensated from a total rewards perspective in many ways for their contributions to our mission, including competitive pay, exceptional health benefits, retirement plans, time off, and a range of recognition and wellness programs. Visit our Benefits at HHMI site to learn more. HHMI is an Equal Opportunity Employer