Scientist, Protein Engineering and Biochemistry

About the role...

We are looking for a self-motivated, curious, collaborative Scientist with broad technical experience in protein engineering and biochemistry. In this role, you will collaborate with Scientists and Research Associates to develop cutting-edge methods for computational protein design, build technology platforms for high-throughput data generation, and characterize novel protein targets. This lab based role is located at our HQ in Cambridge, MA. If you have a desire to contribute to a world changing mission Inari is the place for you! 

As a Scientist, you will...

• Develop and automate novel biochemical and molecular assays, and perform high-throughput screens for protein function, interaction, and expression
• Express and purify recombinant proteins in prokaryotic and cell-free systems
• Design and clone diverse gene libraries using site-directed mutagenesis and PCR-based methods
• Develop, document and deploy standard operating procedures (SOPs)
• Collaborate with scientists and research associates to design experiments, trouble-shoot, and analyze experimental data
• Maintain up to date electronic records and communicate results to stakeholders through written reports and oral presentations

You bring...

• PhD or Master’s degree with at least 4 years of lab experience in a relevant scientific discipline (e.g. biochemistry, bioengineering, genetics, etc.) 
• Understanding of protein structure, folding, stability, function, interaction, and dynamics
• Proficient in common protein stability, interaction, and activity assay formats and analytical instruments
• Experience in protein expression, affinity purification (AKTA/FPLC), and detection by SDS-PAGE / Western blot
• Experience with prokaryotic selection or directed evolution systems, FACS or microfluidics, and fluorescence screening
• Experience with molecular biology and cloning, Gibson assembly, site-directed mutagenesis, and nucleic acid analysis (electrophoresis, PCR and qPCR)
• Excellent time management and organization, professional integrity, adaptability and enthusiasm for new challenges, innate curiosity, and a passion for learning
• A strong sense of purpose and drive to develop unique, high-impact solution

Bonus qualifications...

• Experience with gene editing and CRISPR-Cas technologies
• Experience with Next Generation Sequencing
• Familiarity with Geneious, Benchling, and similar software tools for plasmid design and construction
• An interest in agricultural biotechnology or knowledge of plant molecular biology