Senior Scientist

Employer: Janssen Research & Development, LLC

Job Title: Senior Scientist

Job Code: A011.5288

Job Location: Spring House, PA

Job Type: Full-Time

Job Duties: Promote and apply clinical pharmacology component of clinical trials within the Cardiovascular and Metabolic, Pulmonary Arterial Hypertension, and Neuroscience Therapeutic Areas. Perform and report pharmacokinetic (PK) and pharmacodynamic (PD) analyses. Conduct advanced PK/PD modeling research with emphasis on mechanism-based modeling techniques, systems biology and disease progression models. Integrate knowledge of nonclinical data (e.g. metabolism, BCS classification, pharmacology, safety), PK, PD (e.g. biomarker, efficacy, and/or safety), patient characteristics, disease states, competitive landscape, and drug interactions to influence go/no go decisions, support patient sub-population, dose and dosage regimen selection, and optimize study designs throughout drug development. Support clinical development through model-informed drug development (MIDD), with guidance from senior clinical pharmacology and pharmacometrics (CPP) leaders. Apply regulatory requirements and guidance in drug development undertakings. Serve as CPP Leader on Compound Development Teams (CDT) under supervision, and collaborate with various stakeholders to execute day-to-day operations in the clinical pharmacology domain of assigned programs. Programs may cover all phases of drug development, ranging from pre-New Molecular Entity (NME) declaration through Post-Marketing support. Perform population PK/PD analysis in support of regulatory submissions. Identify opportunities and ways to address drug development questions and issues via linear or nonlinear mixed effects modeling. Use standard PK software to integrate PK/PD and evaluate optimal doses and regimens. Requirements: Employer will accept a Ph.D. degree in Pharmaceutical Sciences, Clinical Pharmacology, Biomedical Engineering or related Biological Sciences field and 1 year of experience in the job offered or a Senior Scientist-related occupation .

This job posting is anticipated to close on 8/1/2024. The Company may however extend this time-period, in which case the posting will remain available on https://www.careers.jnj.com to accept additional applications.

Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance.

Employees may be eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)).

This position is eligible to participate in the Company's long-term incentive program.

Employees Are Eligible For The Following Time Off Benefits

• Vacation - up to 120 hours per calendar year
• Sick time - up to 40 hours per calendar year; for employees who reside in the State of Washington - up to 56 hours per calendar year
• Holiday pay, including Floating Holidays - up to 13 days per calendar year
• Work, Personal and Family Time - up to 40 hours per calendar year
  
  

Additional information can be found through the link below.

For additional general information on Company benefits, please go to: - https://www.careers.jnj.com/employee-benefits

Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

For more information on how we support the whole health of our employees throughout their wellness, career and life journey, please visit www.careers.jnj.com .]