What are the responsibilities and job description for the Fellow, No Fringe Benefits position at Massachusetts General Hospital?
We are recruiting highly qualified post-doctoral research fellows to join the preclinical laboratories of the Center for Precision Imaging at Massachusetts General hospital (www.precisionimaging.center) to pursue research in basic PET imaging and treatment of cancer. Our center is at the forefront of personalized PET molecular imaging, and we are working to pioneer novel precision imaging and therapy approaches. We have a long-standing interest in developing and translating targeted biological PET probes for improved tumor characterization for personalizing cancer treatment and autoimmune conditions. Over the past decade, we have produced many PET and optical imaging probes for assessing immune system activation, receptor imaging, imaging of the tumor microenvironment and interrogation of metabolome. Our group has led some of the first efforts to diagnose therapeutic resistance through receptor imaging and feedback loop signaling, monitor and predict the immune response in cancer immunotherapy and utilize targeted imaging to determine effective therapy dosing, among others. These efforts have led to two first-in-human imaging agents, most recently 68Ga-NOTA-hGZP for imaging granzyme B, currently in open trials for clinical validation.
The selected candidate will get the opportunity to interact and develop research ideas in collaboration with accomplished scientists at Martinos Center for Biomedical Imaging and clinician scientist at MGH Division of Nuclear Medicine and Molecular Imaging. The appointment at the Massachusetts General Hospital and Harvard Medical School research fellow will be for 1-2 years with possibility of extension based on performance and the availability of funding.
Qualifications:
The successful candidate will be a highly motivated and enthusiastic researcher with a desire to begin an independent career related to pre-clinical or translational quantitative molecular imaging and treatment of cancer. Qualified candidates will have an MD, MD/PhD or PhD in biology, biomedical engineering, molecular imaging, or a related field. Prior experience in 1) basic science of cancer development, characteristics, and tumor biomarkers; 2) microPET image acquisition and analysis; 3) working with small animals and creation of animal models; 4) wet lab skill including cell culture, cell and tissue immunohistochemistry and immunofluorescence staining, western blot, and flow cytometry are highly desired. A track record of publication and excellent written and oral English communication skills are required. The candidate should have a strong interest and commitment to research.
List of Skills/Abilities/Competencies
- Excellent verbal and written communication skills
- A track record of productive research and publications
- Interest in cancer molecular imaging and radiotheranostics
Interested applicants should send a cover letter describing research interest and experience, an updated CV, and names and contact information of three references to: Umar Mahmood, MD PhD (Email: umahmood@mgh.harvard.edu). Please contain "Research Fellow Application: Your Name" in the e-mail subject line.
EDUCATION:
Required:
- MD, MD/PhD or PhD in chemistry, biochemistry, biomedical engineering, molecular biology or related fields (Required)
Preferred:
- Previous experience with preclinical PET imaging and/or radio-labeling with radiometals
- Experience with image analysis
- Experience with routine laboratory techniques such as cell culturing, Western blot, IHC, and flowcytometry is preferred.
