At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs, but few options.
What We Do:Neurocrine Biosciences is a neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs, but few options. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, endocrine and psychiatric disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, Parkinson's disease, endometriosis* and uterine fibroids*, as well as clinical programs in multiple therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science. *in collaboration with AbbVie
About the Role:
Work on the design, synthesis and characterization of novel peptides to discover next-generation peptide-based therapeutics. Use expert synthetic knowledge and proven design and synthetic accomplishments to enable progress in peptide-related drug discovery._
Your Contributions (include, but are not limited to):Synthesis, purification and characterization of peptides, small proteins and chemically-modified analogs using state-of-the-art synthesis, purification, analytical and biophysical techniques
Participate in projects and teams towards agreed upon goals, ultimately working towards candidate peptide nomination
Independent data-driven optimization of peptide SAR
Aid in lab setup, instrument purchase, installation and ongoing lab operations
Effective communication of scientific rationale, results and interpretation at project, team and departmental meetings, contributing to strategic discussions
Active collaboration and sharing of expertise with colleagues
Performs other job related duties as assigned
BS/BA degree in chemistry or closely related field and 10 years' experience in peptide OR synthesis, purification, and characterization, a proven track record in peptide technologies and hit discovery, strong knowledge in peptide chemistry and medicinal chemistry, experience in complex synthetic strategies and modern peptide chemistry techniques, proficiency in using analytical instruments
MS/MA degree in chemistry or closely related field and 8 years of similar experience as noted above OR
PhD in organic chemistry, or related field, with 0-3 subsequent years of experience in the field
Proficient in all aspects of modern peptide synthesis, purification and analysis; capable of immediate independent laboratory work on solid- and solution-phase chemistry
Strong publication record of accomplishment
Strong understanding of peptide structure and associated biophysical techniques to assess peptide structure, stability and behavior in solution
Experience in bioconjugation and time-extension strategies for peptides
Excellent interpersonal skills with strong oral and written communication abilities
Assimilates data and research findings outside of Neurocrine for application to new scientific projects
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Neurocrine Biosciences is an EEO/AA/Disability/Vets employer.
We are committed to building a diverse, equitable, and inclusive workplace, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don't line up to exactly what we have outlined in the job description.
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The annual base salary we reasonably expect to pay is $86,200.00-$125,050.00. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. In addition, this position offers an annual bonus with a target of 20% of the earned base salary and eligibility to participate in our equity based long term incentive program. Benefits offered include a retirement savings plan (with company match), paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.
Salary : $86,200 - $125,050
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