Scientist - Immunology/Cell Biology

Orca Bio
Menlo, CA Full Time
POSTED ON 6/12/2024

More than one million people in the United States today are fighting blood cancer. While a traditional allogeneic stem cell transplant has been the best hope for many, the transplant itself can prove fatal or lead to serious conditions, such as graft vs. host disease. Orca Bio is redefining the transplant process by developing next-generation cell therapies with the goal of providing significantly better survival rates with dramatically fewer risks. With our purified, high-precision investigational cell therapies we hope to not only replace patients' blood and immune systems with healthy ones, but also restore their lives.


In this one-year assignment, with possibility for extension, we are looking for recent Ph.D graduates to lead projects focused on studying the fundamental biology of regulatory T cells (Tregs) and their role in immune regulation following adoptive transfer.


Key responsibilities include:

- Investigating the cellular and molecular mechanisms underlying Treg function in inflammation and autoimmunity.

- Utilizing in vitro cell-based assays and mouse models to advance our understanding of Treg biology.

- Collaborating with interdisciplinary teams to explore therapeutic opportunities for autoimmune diseases and immune-related disorders.

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Required Qualifications:
  • Ph.D. in Immunology, Molecular Biology, Cell Biology, or related field.
  • Strong background in Treg or T cell biology and immunology.
  • Experience with in vitro cell-based assays and mouse models.
  • Demonstrated ability to independently design, execute, and interpret experiments.
  • Excellent communication and interpersonal skills.
  • Track record of scientific productivity, including peer-reviewed publications, is desirable.


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The anticipated annual salary range for this U.S. based job is $75,000– $100,000. The final offer will be based on professional experience previously in this role/industry, education, geographic location, internal equity, and other job-related factors as permitted by law. Actual compensation may vary. You may also be eligible to receive pre-IPO equity, in addition to medical, dental, vision, PTO, 401(k) plan, life and accidental death and disability coverage, and parental leave benefits. Total compensation will be determined at the Company's sole discretion. 


Who we are


We are driven by a passion for science and compassion for patients. We act with urgency to ensure our treatments are one day accessible to all who need them.


We live by our core values of passion, courage, and integrity. Excellence in our work means the chance to unlock a better quality of life for our patients, and with that comes tremendous responsibility.


We innovate on a path that hasn’t been paved. We embrace an entrepreneurial spirit and take calculated risks to achieve our mission. We aren’t afraid to ask “why not” and challenge the status quo.


We maintain a start-up culture of camaraderie and leadership by example, regardless of title.


We’re proud to be an equal opportunity employer, and recognize that celebrating our differences creates stronger, lasting solutions that better serve our team, our patients and their healthcare providers.


Notice to staffing firms


Orca Bio does not accept resumes from staffing agencies with which we do not have a written agreement and specific engagement for a particular opening. Our employment activities, inquiries and offers are managed through our HR/Talent team, and all candidates are presented through this channel only. We do not accept unsolicited resumes.

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