Research Assistant | Laboratory of Systems Cancer Biology

Rockefeller University
New York, NY Full Time
POSTED ON 4/3/2023 CLOSED ON 4/27/2023

What are the responsibilities and job description for the Research Assistant | Laboratory of Systems Cancer Biology position at Rockefeller University?

Organization Overview

Cancer remains a daunting problem despite decades of active research into its molecular causes. Such studies have predominantly focused on the earliest stages of cancer progression, such as the formation of a cancer or genes involved in the growth of the primary tumor. In humans afflicted by cancer, the primary tumor is typically surgically resected or eliminated by radiation. Vast numbers of patients, nonetheless, die of cancer as a result of metastasis or the spread of cancer cells from the primary tumor site to distal organs. This process is, in fact, the overwhelming cause of death from cancer, and its occurrence changes a patient's prognosis to incurable. Despite its vast clinical significance and inherently fascinating underlying biology, the metastatic program is poorly understood both at the molecular level and at the cellular/tissue micro-environment levels. Our laboratory employs a multi-disciplinary approach involving molecular, biochemical, computational, imaging, and clinical association methods to characterize the critical regulatory pathways that mediate the steps of this process. By implanting human cancer cells obtained from patients with breast or colon cancer into recipient mice, we study and interfere with the various stages of metastasis. By comparing human cancer cells that are highly metastatic to those that fail to metastasize, we have uncovered a set of small RNA molecules (microRNAs) that suppress metastasis. Our future work is aimed at gaining a better understanding of the mechanisms by which these microRNAs block metastasis. Our hope is that a better understanding of this process will enhance our therapeutic arsenal against it.

Overview

The Research Assistant will perform routine tasks in a research environment thereby providing essential assistance to Graduate Students and Post docs.

Responsibilities

Responsibilities include:

  • Performing advanced laboratory research activities including animal handling
  • Assisting lab researchers in ongoing experiments including molecular biology
  • Maintaining lab records and detailed protocols
  • Participating in the design of research studies
  • Compiling and analyzing research data using relevant computer software

Qualifications

Bachelor's degree required.

 

The Rockefeller University is an Equal Opportunity Employer - Minorities/Women/Disabled/Veterans.

Compensation Range: Min

USD $46,000.00/Yr.

Compensation Range: Max

USD $50,000.00/Yr.

Salary : $46,000 - $50,000

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