Drug Discovery Team SRA II

IND (Neurodegenerative Dis)

Full Time

76480BR

Job Summary

This position exists to support our animal-based drug discovery studies by coordinating with their supervisor and collaborating with researchers and animal-care staff. The person in this position will execute and document animal experiments in ABSL1-ABSL2* conditions for drug discovery studies by coordinating with his/her supervisor and with research and animal care staff. In coordination with his/her supervisor, this person will be responsible for ensuring that animals in drug discovery studies are provided with the correct formulation of medicated diet. This person will be responsible for identifying potential problems with drug discovery studies, forming a draft plan for addressing these and promptly communicating these to her/his supervisor. In coordination with his/her supervisor, this person will be responsible for regularly updating key stakeholders in the drug discovery group on ongoing projects. Additionally, in coordination with his/her supervisor, this person will be expected to draft and/or optimize Standard Operating Procedures for all assigned duties.

This position also contributes to a range of animal experiments conducted at the IND Animal Facility, which includes procedures such as bioluminescence imaging, brain inoculation, wound closures, perfusions, sample collections, necropsies, injections, anesthesia, gavage, stereotaxic surgeries, and neurodegenerative diagnosis. This position is responsible for maintaining proficiency of all previously utilized procedures, as well as continued education and training in new procedures and techniques. The position is required to conduct all animal procedures without causing any undue stress to animals, while maintain accurate records, that document any animal distress, anesthesia administration, unexpected outcomes, and deviations from SOPs. Good records must be maintained in the electronic database, as well as in hard copy.

This position is also responsible for performing inoculations and neurological diagnoses for all of our basic science research groups. This person will also be trained in special procedures including but not limited to; CSF collection in mice and rats, oral gavage, PK study acclimation, and initiation and completion, comprehensive cataloging of all tissue samples for transport to mission bay (10's of thousands of samples), as well as training of new employees. Additionally, this person can devote up to 20% of their time assisting other critical needs of the Animal facility, including but not limited to; cage wash assistance, colony maintenance and procedures, husbandry duties including cage changes and animal welfare checks, or any other tasks assigned by the supervisor which are deemed critical to the needs of the animal facility.

The final salary and offer components are subject to additional approvals based on UC policy.

To see the salary range for this position (we recommend that you make a note of the job code and use that to look up): TCS Non-Academic Titles Search (ucop.edu)

Please note: An offer will take into consideration the experience of the final candidate AND the current salary level of individuals working at UCSF in a similar role.

For roles covered by a bargaining unit agreement, there will be specific rules about where a new hire would be placed on the range.

To learn more about the benefits of working at UCSF, including total compensation, please visit: https://ucnet.universityofcalifornia.edu/compensation-and-benefits/index.html

Department Description

The UCSF Institute for Neurodegenerative Diseases is entirely dedicated to research on neurodegenerative diseases such as multiple systems atrophy, chronic traumatic encephalopathy, and Alzheimer's. Its animal facility houses one of the largest colony of animals involved in prion disease research in the world. It is also one of the largest transgenic facilities dedicated to a single group of diseases. It produces over 10,000 transgenic animals per year carrying diverse modifications of a single gene or multiple genes at once. Our mission is to find currently non-existent cures for these debilitating neurodegenerative diseases affecting large segments of the population. Our entire staff is dedicated to this mission, operating on the cutting-edge of science, while maintaining the highest standards of animal care and welfare. The IND is directed by Nobel Laureate Stanley Prusiner, MD.

Required Qualifications

• BA/BS in a related science and one or more years of recent, directly related work experience, utilizing the techniques or methods required by the position; and/or equivalent experience/training.
• California Drivers License
• Excellent communication and organizational skills
• Strong sense of responsibility and transparency with all aspects of job
• Attention to detail
• Basic laboratory skills
• Basic computer skills
• Ability to read and follow detailed scientific literature and directions, including literature on experimental methods and detailed Standard Operating Procedures

Preferred Qualifications

• AAALAS certification
• 1 years work in an Animal Care and Use Program
• 1 years working in a ABSL1 or ABSL2 environment
• 1 years work experience handling rodents
• Experience in basic rodent biomethodology techniques (anesthesia, injections, bleeding, etc.).
• Experience reporting abnormal signs in rodents (experience in nervous system abnormalities highly preferred)
• Working knowledge of mouse genetics and nomenclature
• Experience in administering drugs to rodents

About UCSF

The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. It is the only campus in the 10-campus UC system dedicated exclusively to the health sciences. We bring together the world's leading experts in nearly every area of health. We are home to five Nobel laureates who have advanced the understanding of cancer, neurodegenerative diseases, aging and stem cells.

Pride Values

UCSF is a diverse community made of people with many skills and talents. We seek candidates whose work experience or community service has prepared them to contribute to our commitment to professionalism, respect, integrity, diversity and excellence - also known as our PRIDE values.

In addition to our PRIDE values, UCSF is committed to equity - both in how we deliver care as well as our workforce. We are committed to building a broadly diverse community, nurturing a culture that is welcoming and supportive, and engaging diverse ideas for the provision of culturally competent education, discovery, and patient care. Additional information about UCSF is available at

Join us to find a rewarding career contributing to improving healthcare worldwide.

Equal Employment Opportunity

The University of California San Francisco is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran or disabled status, or genetic information.

Organization

Campus

Job Code and Payroll Title

009617 SRA 2 NEX

Job Category

Research and Scientific

Bargaining Unit

University Professional Technical Employees - Research Support Professionals Unit (UPTE-RX)

Employee Class

Career

Percentage

100%

Location

TBD

Shift

Days

Shift Length

8 Hours

Additional Shift Details

Usually M-F or W-Sun depending on project needs. Hours 7am-3:30pm. Occasional atypical working hours may be needed depending on project needed