Pre-Clinical Drug Safety Scientist

Pre-Clinical Drug Safety Scientist in Cambridge, MA
Full Time Direct Hire

Salary: $77-91k/year

Company Description

This position is with an International life sciences CRO, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. They work with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate.

Some of the Your Responsibilities:

• Conduct in vitro assays, including biochemical, traditional cell culture and cardiomyocyte functional assays
• Use molecular & cellular biology and next generation sequencing technology to investigate mechanisms of drug-induced toxicity
• Collaborate with investigative toxicologists to make safer medicines
• Provide hands on support for NGS library prep and sequencing data generation
• Validate new biomarkers for drug safety risk assessment

Skills or Requirements:

• Experience with advanced cell culture approaches with cell lines, primary cells, and iPSC derived cells.
• Cell and molecular biology skills including development of reporter assays, application of knock-out, knock-down technology, gene expression analysis, and biomarker assay development and validation. Experience with next generation sequencing and bioinformatics analysis is a plus.
• Experience working in a matrixed team environment at a pharmaceutical company and/or CRO
• Broad scientific knowledge including pharmacology, toxicology, pathology, physiology and biochemistry.

Education:

• Master's degree in molecular biology, pharmacology, toxicology, or a related discipline; new PhD candidate is a plus

What’s In It For You?

Position is full-time, Monday - Friday 8:00am - 5:00pm. Candidates currently living within a commutable distance of Cambridge, MA are encouraged to apply. Excellent full time benefits including comprehensive medical coverage, dental, and vision options

• Life and disability insurance
• 401(k) with company match
• Paid vacation and holidays

A M/F, Disabled, and Veteran Equal Employment Opportunity and Affirmative Action employer.

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